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C9373 Sigma

CP-96345

≥98% (HPLC)

Synonym: (2S,3S)-cis-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine

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Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

CP-96345 is a selective NK1 antagonist. CP96345 inhibits substance P-induced salivation in the rat by classical in vivo bioassay, but did not inhibit NK2, NK3, or numerous other receptors.

Features and Benefits

This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Safety Information

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Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Tachykinin Receptors

The tachykinins represent a large family of peptides whose common structural feature is the C-terminal amino acid sequence Phe-X-Gly-Leu-Met-NH2. Substance P (SP), neurokinin A (NKA), neurokinin B (N...
Keywords: Atomic absorption spectroscopy, Clinical, Diseases, Gastrointestinal, Gene expression, Inflammation, Neurotransmission, Schizophrenia, Transduction

Peer-Reviewed Papers
15

References

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