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C9377 Sigma

Chenodeoxycholic acid

≥97%

Synonym: 3α,7α-Dihydroxy-5β-cholanic acid, 5β-Cholanic acid-3α,7α-diol, Chenodiol

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Properties

Related Categories Anionic Detergents, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents, Cell Culture,
description   anionic
InChI Key   RUDATBOHQWOJDD-BSWAIDMHSA-N
assay   ≥97%
CMC   3
mp   165-167 °C(lit.)
Gene Information   human ... CYP1A2(1544)

Description

Application

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Chenodeoxycholic acid has been used in a study to assess its effects as a long-term replacement therapy for cerebrotendinous xanthomatosis (CTX). It has also been used in a study to investigate its effects on the small-intestinal absorption of bile acids in patients with ileostomies.

Biochem/physiol Actions

Bile Acid

General description

Chenodeoxycholic acid is a bile acid synthesized in the liver from cholesterol.

Packaging

100 mg in glass bottle

5, 25 g in glass bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C9377.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C9377.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
FZ1980000
Protocols & Articles

Articles

Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, Transcription

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

Bile acids are increasingly recognized as playing an important signaling role in the control of immune response and energy metabolism. Recently, there has been interest in measuring bile acid concent...
Clare Glicksman, Michael Wright, Dave Bell, and Anders Fridström
Reporter US, Volume 33.1
Keywords: Bacterial conjugations, Clinical, High performance liquid chromatography, Hormones, Mass spectrometry, Metabolism, Separation, Thin layer chromatography

HPLC Analysis of Bile Acids on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Bile Acids on Ascentis® Express C18
Keywords: Chromatography, Clinical, High performance liquid chromatography

LC/MS Analysis of Bile Acids and Their Conjugates on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Bile Acids and Their Conjugates on Ascentis® Express C18
Keywords: Chromatography, Clinical, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

Related Products

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Product #

Description

Add to Cart

614122 Chenodeoxycholic acid-2,2,4,4-d4, 98 atom % D, 98% (CP)
617024 Chenodeoxycholic-2,2,3,4,4-d5 acid, 98 atom % D

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