C9658 Sigma

Carboxypeptidase G from Pseudomonas sp.

lyophilized powder, ≥3 units/mg protein

DOWNLOAD MSDS (PDF)

Synonym: γ-Glutamyl hydrolase

Description

Preparation Note

Chromatographically purified

Unit Definition

One unit will hydrolyze 1.0 μmole of L-glutamic acid from (+)amethopterin per min at pH 7.3 at 30 °C.

Physical form

Contains sodium acetate salt.

Application

Carboxypeptidase G from Pseudomonas sp., or γ-Glutamyl hydrolase, has been used in a study to assess the role of the putidaredoxin COOH-terminus in P-450cam (cytochrome m) hydroxylations. Carboxypeptidase G from Pseudomonas sp. has also been used in a study to investigate the effects of nitric oxide on pemetrexed cytotoxicity via NO‑cGMP signaling in lung adenocarcinoma cells.

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