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C9801 Sigma

Casein, N,N-dimethylated from bovine milk

essentially salt-free, lyophilized powder

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Properties

Related Categories Biochemicals and Reagents, Enzymes, Inhibitors, and Substrates, General Protease Substrates, Proteolytic Enzymes and Substrates
form   essentially salt-free, lyophilized powder
storage temp.   −20°C

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Packaging

1, 5, 25, 50 g in poly bottle

Preparation Note

Reductive methylation of C5890 by the method of Cabacungan, J.C., et al., Anal. Biochem., 124, 272 (1982).

Application

Casein, N,N-dimethylated from bovine milk can be used in assays to detect and help determine the functional role of tissue transglutaminase (tTG) in disease. In particular, Casein, N,N-dimethylated has been used in the mechanic and kinetic analysis of tTG on protein substrates, which may be linked to neurodegenerative disease.

This preparation has less than 10% reactivity with 2,4,6-trinitrobenzenesulfonic acid (TNBS) compared to non-methylated casein.

Protease substrate that has been used to assay basilase and a subtilisin analog that had been produced by site-directed mutagenesis.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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06693 Timestrip Plus -20 °C

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