CGK733
≥98% (HPLC), solid
DOWNLOAD MSDS (PDF)Synonym:
2,2-
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Empirical Formula (Hill Notation) C23H18Cl3FN4O3S
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Molecular Weight 555.84
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MDL number MFCD09038682
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PubChem Substance ID 24724454
Properties
| Related Categories | ATM, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Protein Kinase Inhibitors, |
| assay | ≥98% (HPLC) |
| form | solid |
| color | off-white |
| solubility | DMSO: >5 mg/mL |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
Originally published as a selective ataxia telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) kinase inhibitor, which causes reversible reprogramming of cellular lifespan, conferred robust growth to senescent cells that had ceased proliferation.
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