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C9872 Sigma

Anti-CIRBP (121-135) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-CIRP, Anti-Cold-inducible RNA-binding protein

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Properties

Related Categories Alphabetical Index, Antibodies, CI-CN, Primary Antibodies
species reactivity   human
application(s)   western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~19 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CIRBP(1153)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 121-135 of human CIRBP

General description

CIRBP is expressed in normal testes and downregulated after heat stress caused by cryptorchidism, varicocele or environmental temperatures.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Application

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if. Anti-CIRBP antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:2000.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

Extracellular CIRBP is a detrimental factor in stimulating inflammation to cause neuronal damage in cerebral ischemia. It may have a protective effect on testicular injury after testicular torsion/detorsion when upregulated. Downregulation of CIRBP has been shown to increase germ cell apoptosis.

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Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

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