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C9915 Sigma

ω-Conotoxin GVIA

≥97% (HPLC)

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Properties

Related Categories Calcium Channel Modulators, Cell Biology, Cell Signaling and Neuroscience, Ion Channel Modulating Peptides, Ion Channels,
assay   ≥97% (HPLC)
composition   Peptide content, ~70%
storage temp.   −20°C
Gene Information   human ... CACNA1B(774)
mouse ... CACNA1B(12287)
rat ... CACNA1B(257648)

Description

Amino Acid Sequence

Cys-Lys-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys-Tyr-NH2 [Disulfide Bridges: 1-16, 8-19, 15-26]

Application

Powerful probe for exploring the vertebrate pre-synaptic terminal.

Other Notes

Lyophilized from 0.1% TFA in H2O

Biochem/physiol Actions

Blocks specific voltage-dependent N-type Ca2+ channels in neurons, but not in muscle; does not bind to either the dihydropyridine or verapamil binding sites; peptide first isolated from the marine snail Conus geographus L.

Price and Availability


Amplified Detection

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
GL2665050

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

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Product #

Description

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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