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D0260 Sigma

N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt

≥97% (HPLC), powder

Synonym: Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism,
InChI Key   KRBZRVBLIUDQNG-JBVYASIDSA-M
assay   ≥97% (HPLC)
form   powder
impurities   ≤0.5% cyclic AMP and 2′-O-monobutyryl-cyclic AMP
  ≤3% N6-monobutyryl-cyclic AMP
color   white
solubility   H2O: soluble100 mg/mL
storage temp.   −20°C

Description

Biochem/physiol Actions

Cell-permeable cAMP analog that activates cAMP dependent protein kinase (PKA).

Caution

Loses 2′-O-butyryl group at pH 8.5

Packaging

25, 100 mg in poly bottle

5 mg in glass bottle

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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DISCOVER Bioactive Small Molecules

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
ES5055500
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Cyclic Nucleotides

Transmission of an extracellular signal across the cell membrane is initiated by activation of many types of hormone and neurotransmitter receptors, such as G-protein coupled receptors (GPCRs), and c...
Keywords: Antivirals, Cancer, Cardiovascular, Cellular processes, Diabetes, Diseases, Hormones, Neurotransmitters

Peer-Reviewed Papers
15

References

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