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D0315 Sigma

Dtk/Fc Chimera human

≥90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym: Developmental Tyrosine Kinase

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience,
recombinant   expressed in NSO cells
assay   ≥90% (SDS-PAGE)
form   lyophilized powder
mol wt   monomer calculated mol wt 69 kDa
  mol wt 100-110 kDa by SDS-PAGE (reducing)
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   human ... TYRO3(7301)

Description

Analysis Note

Measured by its ability to bind recombinant human Gas6.

Biochem/physiol Actions

Receptor tyrosine kinase that binds vitamin K-dependent protein Gas6, leading to cell proliferation, migration, or the prevention of apoptosis.

General description

Extracellular domain of human Dtk (amino acid 1-428) fused to carboxy-terminal 6X histidine-tagged Fc region of human IgG1.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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