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D052 Sigma

GBR 12909 dihydrochloride

solid, ≥98% (HPLC)

Synonym: 1-(2-[bis(4-Fluorophenyl)methoxy]ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride

  • CAS Number 67469-78-7

  • Empirical Formula (Hill Notation) C28H32F2N2O · 2HCl

  • Molecular Weight 523.49

  •  MDL number MFCD00055193

  •  PubChem Substance ID 24277909

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors, Cell Biology,
InChI Key   MIBSKSYCRFWIRU-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
color   white
solubility   DMSO: >5 mg/mL (Solutions freshly prepared daily)
Gene Information   human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)

Description

Biochem/physiol Actions

Highly selective dopamine reuptake inhibitor with behavioral effects similar to cocaine.

Packaging

25, 100, 250 mg in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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