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D0565 Sigma

Digoxin-BSA bovine

lyophilized powder

Synonym: Digoxin-BSA

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Properties

Related Categories Albumin, Biochemicals and Reagents, Modified Albumins, Proteins and Derivatives
form   lyophilized powder
extent of labeling   ~10 mol Digoxin per mol albumin
storage temp.   2-8°C
Gene Information   cow ... ALB(280717)

Description

Biochem/physiol Actions

Antigen-protein conjugate.

Physical form

Lyophilized from 0.06 M Tris

Application

Digoxin-BSA bovine is a cardioactive glycoside which can increase intracellular calcium concentration through Na+/K+-ATPase pump inhibition. Digoxin has been used in treatments of heart related disease and also studies of cancer treatments. It has shown the ability to inhibit prostate cancer cell growth, but has also shown a reduction in the efficiency of chemotherapy (reduced drug absorption) by increasing the amount of P-glycoprotein (Pgp).

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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