|Related Categories||A to C, Adenylate cyclase, Adenylyl Cyclase Inhibitors, Bioactive Small Molecules, Biochemicals and Reagents,|
|solubility||H2O: soluble24 mg/mL|
Potent inhibitor of adenylyl cyclase. Not cell-permeable. IC50 = 40 nM in detergent-dispersed rat brain preparation.
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for MALDI MS, ≥98.0% (HPLC)
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for MALDI MS
≥98% (HPLC), powder
Adenosine 3':5'-monophosphate (cAMP) modifies cell function in all eukaryotic cells, principally through the activation of cAMP-dependent protein kinase (PKA), but also through cAMP-gated ion channel...
Keywords: Catalysis, Cell proliferation, Detergents, Diabetes, Gene expression, Gluconeogenesis, Hormones, Ligands, Neurotransmission, Recombination, Transduction
Adenylyl Cyclases. Johnson, R.A., S. Offermanns and W. Rosenthal Encyclopedic Reference of Molecular Pharmacology Heidelberg/Berlin , (2003)
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