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D129 Sigma

R-(+)-DIOA

≥98% (HPLC), solid

Synonym: R(+)-Butylindazone, R-(+)-[(2-n-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]acetic acid

  • CAS Number 81166-47-4

  • Empirical Formula (Hill Notation) C20H24Cl2O4

  • Molecular Weight 399.31

  •  MDL number MFCD00069261

  •  PubChem Substance ID 24277830

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chloride Channel Modulators,
InChI Key   YAWWQIFONIPBKT-FQEVSTJZSA-N
assay   ≥98% (HPLC)
form   solid
optical activity   [α]27/D +18.1°, c = 0.7 in methanol(lit.)
color   white
solubility   H2O: insoluble <0.11 mg/mL
  DMSO: >20 mg/mL
  0.1 M HCl: insoluble
  0.1 M NaOH: soluble
  ethanol: soluble

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Potent [K+,Cl-]-cotransport inhibitor that shows no side effects on the bumetanimide-sensitive [Na+,K+,Cl-]-cotransport system.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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