EMAIL THIS PAGE TO A FRIEND
D131 Sigma

3,5-Dinitrocatechol

solid

Synonym: 3,5-Dinitro-1,2-benzenediol, OR-486

Purchase

Properties

Related Categories Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Type, Enzymes, Inhibitors, and Substrates, Substrate Analogs More...
form   solid
color   yellow
solubility   H2O: slightly soluble0.17 mg/mL
  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble2.8 mg/mL
  0.1 M HCl: slightly soluble
  DMSO: soluble
  aqueous buffer pH > 5: soluble
  ethanol: soluble
storage temp.   2-8°C
Gene Information   human ... COMT(1312)

Description

Application

Chelating reagent used in a sensitive (μM) assay for vanadium.

Biochem/physiol Actions

Selective inhibitor of catechol O-methyl transferase (COMT); penetrates the blood brain barrier and is useful both orally and parenteraly in experiments where inhibition of COMT in the central nervous system is required.

Caution

Photosensitive

Packaging

50, 250 mg in poly bottle

Quality

Solutions may be stored for several days at 4 °C.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

WGK Germany 
3
RTECS 
CZ8947010

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?