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D141 Sigma

Digitonin

Used as non-ionic detergent

Synonym: Digitin

  • CAS Number 11024-24-1

  • Empirical Formula (Hill Notation) C56H92O29

  • Molecular Weight 1229.31

  •  Beilstein Registry Number 78654

  •  EC Number 234-255-6

  •  MDL number MFCD00077729

  •  PubChem Substance ID 24893429

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Culture, Cell Lysis Reagents, Cell Signaling and Neuroscience,
InChI Key   UVYVLBIGDKGWPX-KUAJCENISA-N
optical activity   [α]20/D −54°, c = 2.8 in methanol(lit.)
mol wt   micellar avg mol wt 70,000
aggregation number   60
CMC   <0.5 mM(20-25°C)
mp   230-240 °C (dec.)(lit.)
solubility   H2O: ~5 % (w/v) (solubilized by heating to 95 °C - 98 °C and then cooling to room temp.)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Quality

Preparation is free of water-insoluble constituents.

Application

Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3462 6.1 / PGIII
WGK Germany 
3
RTECS 
IH2050050

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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