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D1626 Sigma

Deoxyribonucleic acid sodium salt from salmon testes

Synonym: DNA, SS-DNA, smDNA



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Formerly listed as Type III


Deoxyribonucleic acid sodium salt has been used in a study to evaluate the cytotoxicity of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin. Deoxyribonucleic acid sodium salt has also been used in a study to develop a simple method for extracting DNA from Cryptosporidium oocysts.

Salmon Sperm Deoxyribonucleic acid (SS-DNA) may be used to study physicochemical interactions of DNA with binding agents, intercalation agents, modification agents, detection agents and compaction agents. Salmon sperm DNA is used to study the loading capacity of magnetic mesoporous silica nanoparticles (M-MSNs) and binding capacities of polymer nanolayer architectures. SS-DNA may be used as substrate for development of DNA detection assays.

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Safety & Documentation

Safety Information

WGK Germany 

Protocols & Articles

Peer-Reviewed Papers


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Acyclovir-induced nephrotoxicity: the role of the acyclovir aldehyde metabolite Gunness, P., et al. Transl. Res. 158, 290-301, (2011)


DNA binding to zwitterionic model membranes. Ainalem ML, Kristen N, Edler KJ, et al. Langmuir 26, 4965-4976, (2010)


Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion. Sundqvist A, Zieba A, Vasilaki E, et al. Oncogene 32(31), 3606-15, (2013)


Light and host-guest inclusion mediated salmon sperm DNA/surfactant interactions. Lin Y, Zhang Y, Qiao Y, Huang J, Xu B. J. Colloid. Interface Sci. 362, 430-438, (2011)


Synthesis and characterization of pore size-tunable magnetic mesoporous silica nanoparticles. Zhang J, Li X, Rosenholm JM, Gu HC. J. Colloid. Interface Sci. 361, 16-24, (2011)


Draft genome sequence analysis of a Pseudomonas putida W15Oct28 strain with antagonistic activity to Gram-positive and Pseudomonas sp. pathogens. Ye L, Hildebrand F, Dingemans J, et al. PLoS ONE 9(11), e110038, (2014)


The role of polymer nanolayer architecture on the separation performance of anion-exchange membrane adsorbers: Part II. DNA and virus separations. Bhut BV, Weaver J, et al. Biotechnol. Bioeng. 108, 2654-60, (2011)


Silver nanoparticles fluorescence enhancement effect for determination of nucleic acids with kaempferol-Al(III). Cao Y, Wu X, Wang M. Talanta 84, 1188-194, (2011)


Cytotoxicity evaluation of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin Shah, R., et al. J. Pharm. Sci. 93, 1070-82, (2004)


New potential antitumoral fluorescent tetracyclic thieno[3,2-b]pyridine derivatives: interaction with DNA and nanosized liposomes. Castanheira EM, Carvalho MS, et al. Nanoscale Res. Lett. 6, 379, (2011)


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GE27-4565-01 Salmon Testes Sonicated DNA, GE Healthcare, 27-4565-01, pack of 1 ea

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