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D1626 Sigma

Deoxyribonucleic acid sodium salt from salmon testes

Synonym: DNA, SS-DNA, smDNA



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Formerly listed as Type III


1, 5, 10 g in poly bottle

250 mg in poly bottle


Deoxyribonucleic acid sodium salt has been used in a study to evaluate the cytotoxicity of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin. Deoxyribonucleic acid sodium salt has also been used in a study to develop a simple method for extracting DNA from Cryptosporidium oocysts.
Deoxyribonucleic acid sodium salt from salmon testes has been used in basal medium for the anaerobic growth of several Bacillus mojavensis strains1 It has been also used as a component of immunoprecipitation (IP) buffer for the Microplate-Based Matrix Chromatin Immunoprecipitation (ChIP).2

Salmon Sperm Deoxyribonucleic acid (SS-DNA) may be used to study physicochemical interactions of DNA with binding agents, intercalation agents, modification agents, detection agents and compaction agents. Salmon sperm DNA is used to study the loading capacity of magnetic mesoporous silica nanoparticles (M-MSNs) and binding capacities of polymer nanolayer architectures. SS-DNA may be used as substrate for development of DNA detection assays.

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Safety & Documentation

Safety Information

WGK Germany 
Protocols & Articles
Peer-Reviewed Papers


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1. Anaerobic Growth of Bacillus mojavensis and Bacillus subtilis Requires Deoxyribonucleosides or DNA Folmsbee, M.J., et al. Appl. Environ. Microbiol. 70, 5252-7, (2004)


2. Renal ischemia-induced cholesterol loading: transcription factor recruitment and chromatin remodeling along the HMG CoA reductase gene. Naito M, Bomsztyk K, and Zager RA Am. J. Pathol. 174(1), 54-62, (2009)


Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion. Sundqvist A, Zieba A, Vasilaki E, et al. Oncogene 32(31), 3606-15, (2013)


Acyclovir-induced nephrotoxicity: the role of the acyclovir aldehyde metabolite Gunness, P., et al. Transl. Res. 158, 290-301, (2011)


DNA binding to zwitterionic model membranes. Ainalem ML, Kristen N, Edler KJ, et al. Langmuir 26, 4965-4976, (2010)


Synthesis and characterization of pore size-tunable magnetic mesoporous silica nanoparticles. Zhang J, Li X, Rosenholm JM, Gu HC. J. Colloid. Interface Sci. 361, 16-24, (2011)


Light and host-guest inclusion mediated salmon sperm DNA/surfactant interactions. Lin Y, Zhang Y, Qiao Y, Huang J, Xu B. J. Colloid. Interface Sci. 362, 430-438, (2011)


Cytotoxicity evaluation of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin Shah, R., et al. J. Pharm. Sci. 93, 1070-82, (2004)


The role of polymer nanolayer architecture on the separation performance of anion-exchange membrane adsorbers: Part II. DNA and virus separations. Bhut BV, Weaver J, et al. Biotechnol. Bioeng. 108, 2654-60, (2011)


New potential antitumoral fluorescent tetracyclic thieno[3,2-b]pyridine derivatives: interaction with DNA and nanosized liposomes. Castanheira EM, Carvalho MS, et al. Nanoscale Res. Lett. 6, 379, (2011)


Silver nanoparticles fluorescence enhancement effect for determination of nucleic acids with kaempferol-Al(III). Cao Y, Wu X, Wang M. Talanta 84, 1188-194, (2011)


Sphingolipids are required for efficient triacylglycerol loss in conjugated linoleic Acid treated adipocytes. Wang W, Fromm M, et al. PLoS ONE 10(4), e0119005, (2015)


Draft genome sequence analysis of a Pseudomonas putida W15Oct28 strain with antagonistic activity to Gram-positive and Pseudomonas sp. pathogens. Ye L, Hildebrand F, Dingemans J, et al. PLoS ONE 9(11), e110038, (2014)


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GE27-4565-01 Salmon Testes Sonicated DNA, GE Healthcare, 27-4565-01, pack of 1 ea
08168 Timestrip Plus 8 °C

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