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D1814 Sigma

Anti-DcR3 antibody produced in rabbit

~0.5 mg/mL, IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-Decoy Receptor 3, Anti-TNFRSF6B, Anti-TR6

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology, Antibodies to Death Receptors,
species reactivity   rat, human, mouse
application(s)   microarray: suitable
  western blot: 1:500-1:1,000 using human heart, brain or kidney lysates
clone   polyclonal
concentration   ~0.5 mg/mL
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt 33 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... TNFRSF6B(8771)
mouse ... Dcr3(497118)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 31-46 of human DcR3 precursor.

General description

It is a member of the tumor necrosis factor receptor superfamily (TR6). DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Physical form

Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.

Application

Anti-DcR3 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:1000 using human heart, brain or kidney lysates.

Features and Benefits

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Biochem/physiol Actions

DcR3 is a soluble decoy receptor that binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis.

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