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D223 Sigma

N,N-Dimethylsphingosine

oil

Synonym: (2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol, 2-Dimethylamino-4-octadecene-1,3-diol, D-erythro-N,N-dimethylsphingosine, D-Erythro-N,N-Dimethylsphingosine, DMS, Dimethylsphingosine, N,N-Dimethylsphingosine

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Properties

InChI Key   YRXOQXUDKDCXME-YIVRLKKSSA-N
form   oil
solubility   DMSO: soluble
  ethanol: soluble
storage temp.   −20°C

Description

Physical form

Clear oil

Biochem/physiol Actions

N,N-Dimethylsphingosine (DMS) is an endogenous metabolite of sphingosine produced in various tissues and tumor cell lines. N,N-Dimethylsphingosine is a potent inhbitor of sphingosine kinase. DMS levels are elevated in the spinal cord, and contributes to allodynia, in a transected-nerve model of neuropathic pain.

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Safety & Documentation

Safety Information

RIDADR 
UN 1170 3/PG 2
WGK Germany 
1
Flash Point(F) 
57 °F
Flash Point(C) 
14 °C

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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