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D3188 Sigma

Anti-DcR2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Decoy Receptor 2, Anti-TRUNDD, Anti-Trail-R4

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology, Antibodies to Death Receptors,
species reactivity   human
application(s)   ELISA: suitable
  immunocytochemistry: suitable
  immunofluorescence: suitable
  immunohistochemistry: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt 36 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... TNFRSF10D(8793)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 249-263 of human DcR2 precursor.

General description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated death domain.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Application

Anti-DcR2 antibody produced in rabbit is suitable for western blot at 1 μg/mL, immunocytochemistry starting at 10 μg/mL, immunohistochemistry starting at 2.5 μg/mL and for immunofluorescence start at 20 μg/mL.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

The receptor does not induce apoptosis due to the presence of a truncated death domain, and its overexpression inhibits TRAIL-induced cell apoptosis.

Price and Availability


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