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D3506 Sigma

Sodium diethyldithiocarbamate trihydrate

Synonym: Cupral, Diethyldithiocarbamic acid sodium salt


Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.


May form insoluble oxidation products in storage. Sensitivity in colorimetric copper determination not usually affected.


Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Features and Benefits

This compound is featured on the Dopamine, Norepinephrine and Epinephrine Synthesis page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

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