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D3658 Sigma

1,9-Dideoxyforskolin from Coleus forskohlii

≥97%, solid

Synonym: 7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one

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Properties

Related Categories Adenylyl Cyclase Activators, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   ZKZMDXUDDJYAIB-OJPJTMFRSA-N
assay   ≥97%
form   solid
optical activity   [α]26/D +93.6°, c = 6.12 in chloroform(lit.)
color   white to off-white
solubility   methanol: soluble28 mg/mL(lit.)
  DMSO: soluble3 mg/mL(lit.)
  chloroform: soluble50 mg/mL
  ethanol: soluble6.6 mg/mL(lit.)
  dilute aqueous acid and base: insoluble(lit.)
storage temp.   −20°C

Description

Application

Useful as a negative control for forskolin.

Biochem/physiol Actions

Biologically inactive forskolin analog. Does not stimulate adenylyl cyclase.

Packaging

1, 5 mg in glass bottle

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Cyclic Nucleotides

Transmission of an extracellular signal across the cell membrane is initiated by activation of many types of hormone and neurotransmitter receptors, such as G-protein coupled receptors (GPCRs), and c...
Keywords: Antivirals, Cancer, Cardiovascular, Cellular processes, Diabetes, Diseases, Hormones, Neurotransmitters

Peer-Reviewed Papers
15

References

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