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D3669 Sigma

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester)

powder

Synonym: DTSP, Di(N-succinimidyl) 3,3′-dithiodipropionate, Dithiobis(succinimidyl propionate), Lomant’s reagent

  • CAS Number 57757-57-0

  • Empirical Formula (Hill Notation) C14H16N2O8S2

  • Molecular Weight 404.42

  •  Beilstein Registry Number 1518074

  •  EC Number 260-931-5

  •  MDL number MFCD00042045

  •  PubChem Substance ID 24893777

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Properties

Related Categories Amine to Amine, Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking,
InChI Key   FXYPGCIGRDZWNR-UHFFFAOYSA-N
form   powder
solubility   chloroform: soluble50 mg/mL
  DMF: soluble
  acetone: soluble
storage temp.   −20°C

Description

Application

Homobifunctional cross-linking reagent containing a cleavable disulfide linkage. Typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).

Caution

Avoid use of reducing agents during coupling reactions.

Features and Benefits

The disulfide linkage is cleavable by mild reduction.

Price and Availability


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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