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D3759 Sigma

Dextran from Leuconostoc mesenteroides

average mol wt 48,000-90,000

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Dextrans, Dextrans for General Research Applications
mol wt   average mol wt 48,000-90,000
solubility   H2O: 50 mg/mL clear to very slightly hazy, colorless to faintly yellow

Description

Application

Use of dextrans as long and hydrophilic spacer arms improves the performance of immobilized proteins acting on macromolecules.

Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants and physical structure components. They may be used as long hydrophilic spacer arms to improve the performance (freedom of movement) of conjugated/bound proteins. Dextrans may be derivatized for use in biosensor systems.
Dextrans of less than 60,000Da are generally considered low molecular weight dextrans. Low molecular weight dextrans are often preferred versus high molecular weight dextrans due to their viscosities, aggregation and permeation properties. High molecular weight, water-soluble, dextran polymers have been used in a wide variety of biomedical applications. Dextran (48,000-90,000) may be used to induce blood aggregation and as a viscosity plasma expander (HVPE).

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Dextran and Related Polysaccharides

Historically, dextrans had been long recognized as contaminants in sugar processing and other food production. The formation of dextran in wine was shown by Pasteur to be due to the activity of micro...
Vicki Caligur
BioFiles 2008, 3.10, 17.
Keywords: Adhesion, Applications, Chromatography, Clinical, Cosmetics, Derivatizations, Diffusion, Filtration, Immobilization, Industries, Ion Exchange, Ligands, Microscopy, Molecular biology, Molecular biology techniques, Nuclear magnetic resonance spectroscopy, Nucleic acid hybridization, Pharmaceutical, Precipitation, Purification, Separation, Size-exclusion chromatography, Spectroscopy, Sulfations, Type

Protocols

Dextran

Dextran is a polymer of anhydroglucose.  It is composed of approximately 95% alpha-D-(1-6) linkages. The remaining a(1-3) linkages account for the branching of dextran.1,2,3 Conflicting data on the b...
Keywords: Centrifugation, Diffusion, Fractionation, Immunoelectrophoresis, Precipitation, Separation

Peer-Reviewed Papers
15

References

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