Synonym: dGTP sodium salt hydrate
|Related Categories||Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Metabolomics, Nucleotide|
|shipped in||dry ice|
Deoxyguanosine 5′-triphosphate (dGTP), a purine deoxynucleotide, is a substrate of DNA polymerase(s) and reverse transcriptases. dGTP is useful to study the distribution, specificity and kinetics of various NTPases and ribonucleotide reductases.
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100 mM (pH 7)
10 mM in H2O
≥95% (HPLC), powder
Clofarabine 5′-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit. Aye Y, Stubbe J. Proc. Natl. Acad. Sci. U. S. A. 108, 9815-9820, (2011)
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