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D4902 Sigma

Dexamethasone

powder, BioReagent, suitable for cell culture, ≥97%

Synonym: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

  • CAS Number 50-02-2

  • Empirical Formula (Hill Notation) C22H29FO5

  • Molecular Weight 392.46

  •  Beilstein Registry Number 2066651

  •  EC Number 200-003-9

  •  MDL number MFCD00064136

  •  PubChem Substance ID 24893906

  • Popular Documents:  FTNMR (PDF)  

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Properties

Related Categories Bioactives and Supplements for Stem Cell Expansion, Bioactives/Supplements, Cell Biology, Cell Culture, Cell Signaling and Neuroscience,
product line   BioReagent
assay   ≥97%
form   powder
potency   4-500 ng/mL
mp   262-264 °C(lit.)
suitability   suitable for cell culture
storage temp.   2-8°C
Gene Information   human ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908)
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Ptgs2(19225), Tnf(21926)
rat ... Ar(24208), Nr3c1(24413), Tnf(24835)

Description

Frequently Asked Questions

Live Chat and Frequently Asked Questions are available for this Product.

Application

An anti-inflammatory glucocorticoid with a range of effects on cell survival, cell signaling and gene expression. Use to study apoptosis, cell signaling pathways and gene expression.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Reconstitution

To prepare 20 μg/ml stock solution, add 1ml absolute ethanol per mg product; gently swirl to dissolve. Add 49 ml sterile medium per ml of ethanol added, while mixing, to acheive final concentration of 20 μg/ml.

Physical form

powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
Hazard Codes (Europe) 
Xn
Risk Statements (Europe) 
Safety Statements (Europe) 
22-26-36/37-45
WGK Germany 
2
RTECS 
TU3980000

Protocols & Articles

Articles

Mitochondrial Stress and ROS

Oxidative stress is implicated in the pathogenesis of lipotoxicity in both animal and human studies. Chronic oxidative stress is linked to insulin resistance in multiple tissues. Oxidative stress is ...
BioFiles 2011, 6.4, 22.
Keywords: Anti-inflammatory agents, Apoptosis, Cancer, Catalog, Cell signaling, Cellular processes, Gene expression, Indicators, Metabolism, Oxidations, Respiratory

Peer-Reviewed Papers

References

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Glucocorticoids Suppress Growth In Neonatal Cardiomyocytes Co-expressing AT(2) And AT(1) Angiotensin Receptors. Porrello, E.R., et al. Nat. Struct. Mol. Biol. 97, 257-65, (2010)

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Dexamethasone and cyclosporin A suppress mast cell-leukocyte cytokine cascades by multiple mechanisms. Wershil, B.K., et al. Int. Arch. Allergy Immunol. 107, 323-324, (1995)

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Effect of dexamethasone on nitric oxide (NO) production by cultured astrocytes. Llanos, S.L., and Roldan, A. Biocell 23, 29-35, (1999)

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Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: role of GITR and GILZ, two dexamethasone-induced genes. Riccardi, C., et al. Cell Death Differ. 6, 1182-1189, (1999)

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Convergent Functional Genomics Of Oligodendrocyte Differentiation Identifies Multiple Autoinhibitory Signaling Circuits. Gobert, R.P., et al. Mol. Cell. Endocrinol. 29, 1538-53, (2009)

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An Essential Role For Dicer In Adipocyte Differentiation. Mudhasani, R., et al. J. Cell. Mol. Med. 110, 812-6, (2010)

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Selective Transcriptional Regulation Of Aromatase Gene By Vitamin D, Dexamethasone, And Mifepristone In Human Glioma Cells. Yague, J.G., et al. Endocrinol. Relat. Cancer 35, 252-61, (2009)

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Mifepristone Increases Gamma-retroviral Infection Efficiency By Enhancing The Integration Of Virus Into The Genome Of Infected Cells. Solodushko, V., and Fouty, B. Gene Ther. 17, 1253-61, (2010)

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Functional Genomics Assays To Study CFTR Traffic And ENaC Function. Almaça, J., et al. Methods Mol. Biol. 742, 249-64, (2011)

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Detecting Reactive Oxygen Species In Primary Hepatocytes Treated With Nanoparticles. Zolnik, B., et al. Methods Mol. Biol. 697, 173-9, (2011)

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Lenalidomide and dexamethasone in transplant-ineligible patients with myeloma. Benboubker L, Dimopoulos MA, Dispenzieri A, et al. N. Engl. J. Med. 371(10), 906-17, (2014)

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Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Martino MM, Mochizuki M, Rothenfluh DA, et al. Biomaterials 30(6), 1089-97, (2009)

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Effects of dexamethasone as a local anaesthetic adjuvant for brachial plexus block: a systematic review and meta-analysis of randomized trials. Choi S, Rodseth R, and McCartney CJ Br. J. Anaesth. 112(3), 427-39, (2014)

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Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways. Kitase Y J. Bone Miner Res. 25(12), 2657-68, (2010)

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Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1. Venkata Lokesh Battula et al Haematologica 94, 173-84, (2009)

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Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Piovan E, Yu J, Tosello V, et al. Cancer Cell 24(6), 766-76, (2013)

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Confirmation of the mantle-cell lymphoma International Prognostic Index in randomized trials of the European Mantle-Cell Lymphoma Network. Hoster E, Klapper W, Hermine O, et al. J. Clin. Oncol. 32(13), 1338-46, (2014)

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Carfilzomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed multiple myeloma: a multicenter, phase 2 study. Bringhen S, Petrucci MT, Larocca A, et al. Blood 124(1), 63-9, (2014)

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Identifying off-target effects and hidden phenotypes of drugs in human cells. Marnie L MacDonald et al Nat. Chem. Biol. 2, 329-37, (2006)

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Reorganization of the nuclear lamina and cytoskeleton in adipogenesis. Verstraeten VL, Renes J, Ramaekers FC, et al. Histochem. Cell Biol. 135(3), 251-61, (2011)

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Characterization of the drug binding specificity of rat liver fatty acid binding protein. Sara Chuang et al J. Med. Chem. 51, 3755-64, (2008)

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Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability. Giorgio Ottaviani et al J. Med. Chem. 49, 3948-54, (2006)

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Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Markus A Lill et al J. Med. Chem. 48, 5666-74, (2005)

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Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity. Mary Kaileh et al J. Biol. Chem. 282, 4253-64, (2007)

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Molecular characteristics for solid-state limited solubility. Carola M Wassvik et al J. Med. Chem. 51, 3035-9, (2008)

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QSAR study on permeability of hydrophobic compounds with artificial membranes. Masaaki Fujikawa et al Bioorg. Med. Chem. 15, 3756-67, (2007)

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Dexamethasone for antiemesis in laparoscopic gynecologic surgery: a systematic review and meta-analysis. Pham A and Liu G Obstet. Gynecol. 120(6), 1451-8, (2012)

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Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle. Feillet C, Krusche P, Tamanini F, et al. Proc. Natl. Acad. Sci. U. S. A. 111(27), 9828-33, (2014)

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PlGF repairs myocardial ischemia through mechanisms of angiogenesis, cardioprotection and recruitment of myo-angiogenic competent marrow progenitors. Iwasaki H, Kawamoto A, Tjwa M, et al. PLoS ONE 6(9), e24872, (2011)

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Synthesis and biological evaluation of simple methoxylated chalcones as anticancer, anti-inflammatory and antioxidant agents. Babasaheb P Bandgar et al Bioorg. Med. Chem. 18, 1364-70, (2010)

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The living microarray: a high-throughput platform for measuring transcription dynamics in single cells. Rajan S, Djambazian H, Dang HC, et al. BMC Genomics 12, 115, (2011)

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Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bram Baert et al Bioorg. Med. Chem. 15, 6943-55, (2007)

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In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Giorgio Ottaviani et al J. Med. Chem. 50, 742-8, (2007)

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Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450. Vinchi F, Ingoglia G, Chiabrando D, et al. Gastroenterology 146(5), 1325-38, (2014)

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T-typeCa2+ signalling regulates aldosterone-induced CREB activation and cell death through PP2A activation in neonatal cardiomyocytes. Laurent Ferron et al Cardiovasc. Res. 90, 105-12, (2011)

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Evaluation of T and B lymphocyte function in clinical practice using a flow cytometry based proliferation assay. Marits P, Wikström AC, Popadic D, et al. Clin. Immunol. 153(2), 332-42, (2014)

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Best treatment strategies in high-risk multiple myeloma: navigating a gray area. Bianchi G, Richardson PG, and Anderson KC J. Clin. Oncol. 32(20), 2125-32, (2014)

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Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response. Langlais D PLoS Genet. 4(10), e1000224, (2008)

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Interleukin-1 receptor antagonist modulates the early phase of liver regeneration after partial hepatectomy in mice. Sgroi A PLoS ONE 6(9), e25442, (2011)

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Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. R Scott Obach et al Drug Metab. Dispos. 36, 1385-405, (2008)

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Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities. Patrick Bydal et al Eur. J. Med. Chem. 44, 632-44, (2009)

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Synthesis of novel 3,5-diaryl pyrazole derivatives using combinatorial chemistry as inhibitors of tyrosinase as well as potent anticancer, anti-inflammatory agents. Babasaheb P Bandgar et al Bioorg. Med. Chem. 18, 6149-55, (2010)

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Physicochemical determinants of human renal clearance. Manthena V S Varma et al J. Med. Chem. 52, 4844-52, (2009)

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Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Manthena V S Varma et al J. Med. Chem. 53, 1098-108, (2010)

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Dexamethasone for the prevention of postpericardiotomy syndrome: A DExamethasone for Cardiac Surgery substudy. Bunge JJ, van Osch D, Dieleman JM, et al. Am. Heart J. 168(1), 126-31.e1, (2014)

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Pattern of IGF-1 variants' expression in human cancer cell lines using a novel q-RT-PCR approach. Christopoulos PF, Philippou A, and Koutsilieris M Anticancer Res. 35(1), 107-15, (2015)

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Unveiling adrenal insufficiency can make a difference in elderly adults. Kojima G, Laurel P, Inaba M, et al. J. Am. Geriatr. Soc. 62(12), 2456-7, (2014)

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Perineural vs intravenous administration of dexamethasone: more data are available. Albrecht E, Kern C, and Kirkham KR Br. J. Anaesth. 114(1), 160, (2015)

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Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma. Stewart AK, Rajkumar SV, Dimopoulos MA, et al. N. Engl. J. Med. 372(2), 142-52, (2015)

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IgE-dependent activation of human mast cells and fMLP-mediated activation of human eosinophils is controlled by the circadian clock. Baumann A, Feilhauer K, Bischoff SC, et al. Mol. Immunol. 64(1), 76-81, (2015)

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Pseudo-acute kidney injury secondary to intravenous dexamethasone. Nakajima M, Inoue T, Kato H, et al. Am. J. Kidney Dis. 65(2), 344, (2015)

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Alternatively activated dendritic cells derived from systemic lupus erythematosus patients have tolerogenic phenotype and function. Wu HJ, Lo Y, Luk D, et al. Clin. Immunol. 156(1), 43-57, (2015)

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Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study. Kumar SK, Berdeja JG, Niesvizky R, et al. Lancet Oncol. 15(13), 1503-12, (2014)

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Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance. Nowak D, Liem NL, Mossner M, et al. Exp. Hematol. 43(1), 32-43.e1-35, (2015)

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NFATc1 activity regulates the expression of myocilin induced by dexamethasone. Faralli JA, Clark RW, Filla MS, et al. Exp. Eye Res. 130, 9-16, (2015)

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Ghrelin augments murine T-cell proliferation by activation of the phosphatidylinositol-3-kinase, extracellular signal-regulated kinase and protein kinase C signaling pathways. Lee JH, Patel K, Tae HJ, et al. FEBS Lett. 588(24), 4708-19, (2014)

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Intravitreal controlled release of dexamethasone from engineered microparticles of porous silicon dioxide. Wang C, Hou H, Nan K, et al. Exp. Eye Res. 129, 74-82, (2014)

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Immunoglobulin light chain amyloidosis: 2014 update on diagnosis, prognosis, and treatment. Gertz MA Am. J. Hematol. 89(12), 1132-40, (2014)

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Phase 2 study of carfilzomib, thalidomide, and dexamethasone as induction/consolidation therapy for newly diagnosed multiple myeloma. Sonneveld P, Asselbergs E, Zweegman S, et al. Blood 125(3), 449-56, (2015)

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Phase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemia. Kadia TM, Kantarjian HM, Thomas DA, et al. Am. J. Hematol. 90(2), 120-4, (2015)

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Possible role of lymphocytes in glucocorticoid-induced increase in trabecular bone mineral density. Grahnemo L, Jochems C, Andersson A, et al. J. Endocrinol. 224(1), 97-108, (2015)

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Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells. Jing D, Bhadri VA, Beck D, et al. Blood 125(2), 273-83, (2015)

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Regulation of translation by upstream translation initiation codons of surfactant protein A1 splice variants. Tsotakos N, Silveyra P, Lin Z, et al. Am. J. Physiol. Lung Cell. Mol. Physiol. 308(1), L58-75, (2015)

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An antiapoptotic role for telomerase RNA in human immune cells independent of telomere integrity or telomerase enzymatic activity. Gazzaniga FS and Blackburn EH Blood 124(25), 3675-84, (2014)

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REDD1 deletion prevents dexamethasone-induced skeletal muscle atrophy. Britto FA, Begue G, Rossano B, et al. Am. J. Physiol. Endocrinol. Metab. 307(11), E983-93, (2014)

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Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes. Tuure L, Hämäläinen M, Moilanen T, et al. Scand. J. Rheumatol. 44(1), 74-9, (2015)

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Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models. Zi FM, He JS, Li Y, et al. Cancer Lett. 356(2 Pt B), 443-53, (2015)

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Melatonin ameliorates dexamethasone-induced inhibitory effects on the proliferation of cultured progenitor cells obtained from adult rat hippocampus. Ekthuwapranee K, Sotthibundhu A, Tocharus C, et al. J. Steroid Biochem. Mol. Biol. 145, 38-48, (2015)

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Molecular modulation of estrogen-induced apoptosis by synthetic progestins in hormone replacement therapy: an insight into the women's health initiative study. Sweeney EE, Fan P, and Jordan VC Cancer Res. 74(23), 7060-8, (2014)

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Ischemia postconditioning preventing lung ischemia-reperfusion injury. Cao QF, Qu MJ, Yang WQ, et al. Gene 554(1), 120-4, (2015)

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Hypothalamic-pituitary-adrenal axis in lethal canine Staphylococcus aureus pneumonia. Cortés-Puch I, Hicks CW, Sun J, et al. Am. J. Physiol. Endocrinol. Metab. 307(11), E994-E1008, (2014)

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Atomoxetine prevents dexamethasone-induced skeletal muscle atrophy in mice. Jesinkey SR, Korrapati MC, Rasbach KA, et al. J. Pharmacol. Exp. Ther. 351(3), 663-73, (2014)

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Intravitreal dexamethasone implant [Ozurdex] for the treatment of nonarteritic anterior ischaemic optic neuropathy. Alten F, Clemens CR, Heiduschka P, et al. Doc. Ophthalmol. 129(3), 203-7, (2014)

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JNK and IKKβ phosphorylation is reduced by glucocorticoids in adipose tissue from insulin-resistant rats. Motta K, Barbosa AM, Bobinski F, et al. J. Steroid Biochem. Mol. Biol. 145, 1-12, (2015)

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Postnatal glucocorticoid-induced hypomyelination, gliosis, and neurologic deficits are dose-dependent, preparation-specific, and reversible. Zia MT, Vinukonda G, Vose LR, et al. Exp. Neurol. 263, 200-13, (2015)

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Long-term effect of high-dose dexamethasone with or without low-dose dexamethasone maintenance in untreated immune thrombocytopenia. Din B, Wang X, Shi Y, et al. Acta Haematol. 133(1), 124-8, (2015)

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Multiple myeloma: 2014 Update on diagnosis, risk-stratification, and management. Vincent Rajkumar S Am. J. Hematol. 89(10), 999-1009, (2014)

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Multicenter study of intravitreal dexamethasone implant in noninfectious uveitis: indications, outcomes, and reinjection frequency. Zarranz-Ventura J, Carreño E, Johnston RL, et al. Am. J. Ophthalmol. 158(6), 1136-1145.e5, (2014)

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Medication errors on oral chemotherapy in children with acute lymphoblastic leukemia in a developing country. Oberoi S, Trehan A, and Marwaha RK Pediatr. Blood Cancer 61(12), 2218-22, (2014)

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Bortezomib- and thalidomide-induced peripheral neuropathy in multiple myeloma: clinical and molecular analyses of a phase 3 study. Tacchetti P, Terragna C, Galli M, et al. Am. J. Hematol. 89(12), 1085-91, (2014)

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A randomized clinical trial of intravitreal bevacizumab versus intravitreal dexamethasone for diabetic macular edema: the BEVORDEX study. Gillies MC, Lim LL, Campain A, et al. Ophthalmology 121(12), 2473-81, (2014)

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[A patient with paclitaxel hypersensitivity treated with nab-paclitaxel]. Ouchi A, Ouchi A, Asano M, et al. Gan To Kagaku Ryoho. 41(7), 889-91, (2014)

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Efficacy of betamethasone on the fetal motion and biophysical profile and amniotic fluid index in preterm fetuses. Abbasalizadeh S, Pharabar ZN, Abbasalizadeh F, et al. Pak. J. Biol. Sci. 16(22), 1569-73, (2013)

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[Rapidly progressive AL amyloidosis in a patient with relapsed multiple myeloma after achieving a complete response to tandem autologous PBSCT]. Yagi H, Ozaki S, Sekimoto E, et al. Rinsho. Ketsueki. 54(12), 2171-6, (2013)

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[New and old medications for croup and seizures in children. Oral dexamethasone and buccal midazolam may provide better treatment]. Inge A and Nasta F Lakartidningen. 110(48), 2163, (2013)

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[Serious organ damage and intractable clinical conditions in rheumatic and connective tissue disease--progress in pathophysiology and treatment. Topics: II. Clinical conditions special attention needed to be paid to; 4. Macrophage activating syndrome and hemophagocytic syndrome]. Komagata Y Nippon. Naika Gakkai Zasshi. 102(10), 2639-44, (2013)

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[Management of comorbid diabetes and cancer in the elderly]. Ohashi K Nihon Rinsho. 71(11), 2038-42, (2013)

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Recurrent Central Serous Chorioretinopathy with Dexamethasone Eye Drop used Nasally for Rhinitis. Prakash G, Shephali J, Tirupati N, et al. Middle East Afr. J. Ophthalmol. 20(4), 363-5, (2013)

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[Rapid improvement of fluid retention with lenalidomide plus low-dose dexamethasone for POEMS syndrome relapsed after autologous peripheral blood stem cell transplantation]. Ohashi K, Yokoyama A, Kagoo T, et al. Rinsho. Ketsueki. 54(7), 670-4, (2013)

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[Comparison of antiemesis effects of granisetron, aprepitant and dexamethasone to palonosetron, aprepitant and dexamethasone in treatment of high-emetic risk chemotherapy-induced nausea and vomiting - a retrospective study for efficacy and safety in a single institute]. Osawa H, Goto H, and Myojo T Gan To Kagaku Ryoho. 40(5), 617-21, (2013)

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Dexamethasone added to bupivacaine prolongs duration of epidural analgesia. Naghipour B, Aghamohamadi D, Azarfarin R, et al. Middle East J. Anesthesiol. 22(1), 53-7, (2013)

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[The combination of chronic myeloid leukemia and multiple myeloma in one patient]. Romanenko NA, Bessmel'tsev SS, Udal'eva VIu, et al. Vopr. Onkol. 59(2), 103-10, (2013)

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A case of extramedullary plasmablastic plasmacytoma successfully treated using a combination of thalidomide and dexamethasone and a review of the medical literature. Sekiguchi Y, Asahina T, Shimada A, et al. J. Clin. Exp. Hematop. 53(1), 21-8, (2013)

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Retinoic acid syndrome--cardiac complication. Dhar AK and Barman PK J. Assoc. Physicians India 60, 63-5, (2012)

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[Effects of dexamethasone on expressions of IL-21 and its receptor in lungs of experimental asthma mice]. Gong J, Ren D, Luo Y, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29(6), 561-4, (2013)

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Interleukin-6 neutralization alleviates pulmonary inflammation in mice exposed to cigarette smoke and poly(I:C). Hubeau C, Kubera JE, Masek-Hammerman K, et al. Clin. Sci. 125(10), 483-93, (2013)

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[Epidural pharmacotherapy in the treatment of the pain syndrome in osteochondrosis complicated by intervertebral discs protrusion of lumbar part of the vertebral column]. Khizhniak MV and Priĭmak EV Klin. Khir. (3), 44-6, (2013)

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[Modulation of the effects of dexamethasone in rat skeletal muscle by testosterone]. Trush VV and Soboliev VI Fiziol. Zh. 59(1), 47-55, (2013)

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Clinical snapshot: Corneal edema in a Tennessee walking horse. Tirosh-Levy S Compend. Contin. Educ. Vet. 35(2), E7, (2013)

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[Successful treatment with lenalidomide plus dexamethasone for multiple myeloma complicated with systemic amyloidosis]. Fuchida S, Okano A, Hatsuse M, et al. Rinsho. Ketsueki. 53(11), 1937-9, (2012)

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A new ursane-type triterpenoid glycoside from Centella asiatica leaves modulates the production of nitric oxide and secretion of TNF-? in activated RAW 264.7 cells. Nguyen Xuan Nhiem et al Bioorg. Med. Chem. Lett. 21, 1777-81, (2011)

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Combined application of 17beta-estradiol and progesterone enhance vascular endothelial growth factor and surfactant protein expression in cultured embryonic lung cells of mice. Trotter A Int. J. Pediatr. 2009, 170491, (2009)

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Lenalidomide plus dexamethasone for high-risk smoldering multiple myeloma. Mateos MV, Hernández MT, Giraldo P, et al. N. Engl. J. Med. 369(5), 438-47, (2013)

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Spectrophotometric determination of drugs with iodine. Karuna T, et al. J. Sci. Ind. Res. 65(10), 808, (2006)

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Integrating high-content screening and ligand-target prediction to identify mechanism of action. Daniel W Young et al Nat. Chem. Biol. 4, 59-68, (2008)

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FDA-approved drug labeling for the study of drug-induced liver injury. Minjun Chen et al Drug Discov. Today 16, 697-703, (2011)

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Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay. Yosuke Nishizaki et al Bioorg. Med. Chem. Lett. 19, 4706-10, (2009)

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Virtual screening for the identification of novel nonsteroidal glucocorticoid modulators. Valeria Onnis et al J. Med. Chem. 53, 3065-74, (2010)

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Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Steinert AF Tissue Eng. Part A 15(5), 1127-39, (2009)

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Mesenchymal stem cell proliferation and differentiation on an injectable calcium phosphate-chitosan composite scaffold. Moreau JL Biomaterials 30(14), 2675-82, (2009)

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Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Lourdes Santana et al J. Med. Chem. 51, 6740-51, (2008)

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Aprepitant versus dexamethasone for preventing chemotherapy-induced delayed emesis in patients with breast cancer: a randomized double-blind study. Roila F, Ruggeri B, Ballatori E, et al. J. Clin. Oncol. 32(2), 101-6, (2014)

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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Denis Fourches et al Chem. Res. Toxicol. 23, 171-83, (2010)

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Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. Waldron NH, Jones CA, Gan TJ, et al. Br. J. Anaesth. 110(2), 191-200, (2013)

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Nanosponges encapsulating dexamethasone for ocular delivery: formulation design, physicochemical characterization, safety and corneal permeability assessment. Swaminathan S, Vavia PR, Trotta F, et al. J. Biomed. Nanotechnol. 9(6), 998-1007, (2013)

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Lignans and neolignans from Sinocalamus affinis and their absolute configurations. Liang Xiong et al J. Nat. Prod. 74, 1188-200, (2011)

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The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy. Proserpio V, Fittipaldi R, Ryall JG, et al. Genes Dev. 27(11), 1299-312, (2013)

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Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series. Mike Barker et al J. Med. Chem. 49, 4216-31, (2006)

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Lipid raft- and protein kinase C-mediated synergism between glucocorticoid- and gonadotropin-releasing hormone signaling results in decreased cell proliferation. Wehmeyer L, Du Toit A, Lang DM, et al. J. Biol. Chem. 289(14), 10235-51, (2014)

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Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors. Concettina La Motta et al J. Med. Chem. 52, 1681-92, (2009)

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Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma. Zode GS, Sharma AB, Lin X, et al. J. Clin. Invest. 124(5), 1956-65, (2014)

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How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Alex Avdeef et al J. Med. Chem. 53, 3566-84, (2010)

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Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents. Tadashi Honda et al J. Med. Chem. 54, 1762-78, (2011)

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Developing structure-activity relationships for the prediction of hepatotoxicity. Nigel Greene et al Chem. Res. Toxicol. 23, 1215-22, (2010)

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Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period. Vougogiannopoulou K J. Med. Chem. 51(20), 6421-31, (2008)

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Synthesis and pharmacological evaluation of a selected library of new potential anti-inflammatory agents bearing the gamma-hydroxybutenolide scaffold: a new class of inhibitors of prostanoid production through the selective modulation of microsomal prostaglandin E synthase-1 expression. Maria D Guerrero et al J. Med. Chem. 50, 2176-84, (2007)

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Clinical practice: Acute high-altitude illnesses. Bärtsch P and Swenson ER N. Engl. J. Med. 368(24), 2294-302, (2013)

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Dexamethasone to prevent postoperative nausea and vomiting: an updated meta-analysis of randomized controlled trials. De Oliveira GS, Castro-Alves LJ, Ahmad S, et al. Anesth. Analg. 116(1), 58-74, (2013)

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The effects of perineural versus intravenous dexamethasone on sciatic nerve blockade outcomes: a randomized, double-blind, placebo-controlled study. Rahangdale R, Kendall MC, McCarthy RJ, et al. Anesth. Analg. 118(5), 1113-9, (2014)

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A signaling pathway linking nitric oxide production to heterotrimeric G protein and hydrogen peroxide regulates extracellular calmodulin induction of stomatal closure in Arabidopsis. Li JH Plant Physiol. 150(1), 114-24, (2009)

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Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice. Baerga R Autophagy 5(8), 1118-30, (2009)

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P53 dependent mitochondrial permeability transition pore opening is required for dexamethasone-induced death of osteoblasts. Zhen YF, Wang GD, Zhu LQ, et al. J. Cell Physiol. 229(10), 1475-83, (2014)

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Discovery and optimization of novel 3-piperazinylcoumarin antagonist of chemokine-like factor 1 with oral antiasthma activity in mice. Gang Li et al J. Med. Chem. 53, 1741-54, (2010)

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Induction and suppression of PEN3 focal accumulation during Pseudomonas syringae pv. tomato DC3000 infection of Arabidopsis. Xin XF, Nomura K, Underwood W, et al. Mol. Plant Microbe Interact. 26(8), 861-7, (2013)

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Resveratrol-mediated SIRT-1 interactions with p300 modulate receptor activator of NF-kappaB ligand (RANKL) activation of NF-kappaB signaling and inhibit osteoclastogenesis in bone-derived cells. Mehdi Shakibaei et al J. Biol. Chem. 286, 11492-505, (2011)

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Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Francisco J Prado-Prado et al Bioorg. Med. Chem. 18, 2225-31, (2010)

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cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. Huaqing Liu et al J. Med. Chem. 51, 7094-8, (2008)

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Dexamethasone and risk of bleeding in children undergoing tonsillectomy. Mahant S, Keren R, Localio R, et al. Otolaryngol. Head Neck Surg. 150(5), 872-9, (2014)

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Culture of mouse embryonic stem cells with serum but without exogenous growth factors is sufficient to generate functional hepatocyte-like cells. Karen Pauwelyn et al PLoS ONE 6, e23096, (2011)

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Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents. Babasaheb P Bandgar et al Bioorg. Med. Chem. 17, 8168-73, (2009)

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Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity. Keith Biggadike et al J. Med. Chem. 50, 6519-34, (2007)

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Quinol-4-ones as steroid A-ring mimetics in nonsteroidal dissociated glucocorticoid agonists. John Regan et al J. Med. Chem. 49, 7887-96, (2006)

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Superantigen-induced steroid resistance depends on activation of phospholipase Cβ2. Verhaar AP, Wildenberg ME, Duijvestein M, et al. J. Immunol. 190(12), 6589-95, (2013)

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High-dose chemotherapy plus autologous stem-cell transplantation as consolidation therapy in patients with relapsed multiple myeloma after previous autologous stem-cell transplantation (NCRI Myeloma X Relapse [Intensive trial]): a randomised, open-label, phase 3 trial. Cook G, Williams C, Brown JM, et al. Lancet Oncol. 15(8), 874-85, (2014)

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Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial. Vora A, Goulden N, Mitchell C, et al. Lancet Oncol. 15(8), 809-18, (2014)

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Dexamethasone-loaded poly(D, L-lactic acid) microspheres/poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) micelles composite for skin augmentation. Fan M, Liao J, Guo G, et al. J. Biomed. Nanotechnol. 10(4), 592-602, (2014)

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Does dexamethasone induce more neuropsychological side effects than prednisone in pediatric acute lymphoblastic leukemia? A systematic review. Warris LT, van den Heuvel-Eibrink MM, den Hoed MA, et al. Pediatr. Blood Cancer 61(7), 1313-8, (2014)

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Rapamycin protects mice from staphylococcal enterotoxin B-induced toxic shock and blocks cytokine release in vitro and in vivo. Teresa Krakauer et al Antimicrob. Agents Chemother. 54, 1125-31, (2010)

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Nonsteroidal dissociated glucocorticoid agonists containing azaindoles as steroid A-ring mimetics. Doris Riether et al J. Med. Chem. 53, 6681-98, (2010)

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Imaging progesterone receptor in breast tumors: synthesis and receptor binding affinity of fluoroalkyl-substituted analogues of tanaproget. Hai-Bing Zhou et al J. Med. Chem. 53, 3349-60, (2010)

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Development of a surface plasmon resonance biosensor for real-time detection of osteogenic differentiation in live mesenchymal stem cells. Yi-Chun Kuo et al PLoS ONE 6, e22382, (2011)

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Design and synthesis of new nonsteroidal glucocorticoid modulators through application of an "agreement docking" method. Mike Barker et al J. Med. Chem. 48, 4507-10, (2005)

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Antinociceptive properties of bergenin. Cristiane Metzker de Oliveira et al J. Nat. Prod. 74, 2062-8, (2011)

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Polymerase I and transcript release factor regulates lipolysis via a phosphorylation-dependent mechanism. Aboulaich N Diabetes 60(3), 757-65, (2011)

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Discovery of Potent, Selective, and Orally Bioavailable Alkynylphenoxyacetic Acid CRTH2 (DP2) Receptor Antagonists for the Treatment of Allergic Inflammatory Diseases Crosignani, S.; et al. J. Med. Chem. 20th ed., 54, 7299-7317, (2011)

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Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone. Shah S, King EM, Chandrasekhar A, et al. J. Biol. Chem. 289(19), 13667-79, (2014)

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Effect of a proteasome inhibitor plus steroids on HLA antibodies in sensitized patients awaiting a renal transplant. Aubert O, Suberbielle C, Gauthe R, et al. Transplantation 97(9), 946-52, (2014)

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Targeted inhibition of interleukin-6 with CNTO 328 sensitizes pre-clinical models of multiple myeloma to dexamethasone-mediated cell death. Peter M. Voorhees et al Br. J. Haematol. 145, 481-90, (2011)

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Microbial transformation of isosteviol and bioactivities against the glucocorticoid/androgen response elements. Shwu-Fen Chang et al J. Nat. Prod. 71, 87-92, (2008)

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Acute stress causes rapid synaptic insertion of Ca2+ -permeable AMPA receptors to facilitate long-term potentiation in the hippocampus. Whitehead G, Jo J, Hogg EL, et al. Brain 136(Pt 12), 3753-65, (2013)

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Dexamethasone and haemorrhage risk in paediatric tonsillectomy: a systematic review and meta-analysis. Bellis JR, Pirmohamed M, Nunn AJ, et al. Br. J. Anaesth. 113(1), 23-42, (2014)

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Azaxanthene Based Selective Glucocorticoid Receptor Modulators: Design, Synthesis, and Pharmacological Evaluation of (S)-4-(5-(1-((1,3,4-Thiadiazol-2-yl)amino)-2-methyl-1-oxopropan-2-yl)-5H-chromeno[2,3-b]pyridin-2-yl)-2-fluoro-N,N-dimethylbenzamide and Its Methylene Homologue Weinstein, D. S.; et al. J. Med. Chem. 54, 7318-7333, (2011)

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Identification of the bioactive constituent and its mechanisms of action in mediating the anti-inflammatory effects of black cohosh and related Cimicifuga species on human primary blood macrophages. Cindy L H Yang et al J. Med. Chem. 52, 6707-15, (2009)

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High-throughput evaluation of relative cell permeability between peptoids and peptides. Niclas C Tan et al Bioorg. Med. Chem. 16, 5853-61, (2008)

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Intravitreal administration of dexamethasone-loaded PLGA-TPGS nanoparticles for the treatment of posterior segment diseases. Yang C, Jiang L, Bu S, et al. J. Biomed. Nanotechnol. 9(9), 1617-23, (2013)

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Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production. Chien-Shu Chen et al Bioorg. Med. Chem. 18, 597-604, (2010)

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Synthesis and characterization of nonsteroidal glucocorticoid receptor modulators for multiple myeloma. Andrew R Hudson et al J. Med. Chem. 50, 4699-709, (2007)

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Discovery of potent, selective orally active, nonpeptide inhibitors of human mast cell chymase. Greco, M.N., et al. J. Med. Chem. 50, 1727-1730, (2007)

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Blockade of IL-6 secretion pathway by the sesquiterpenoid atractylenolide III. Tae-Hee Kang et al J. Nat. Prod. 74, 223-7, (2011)

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Identification and characterization of acidic mammalian chitinase inhibitors. Derek C Cole et al J. Med. Chem. 53, 6122-8, (2010)

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Novel synthesis of the hexahydroimidazo[1,5b]isoquinoline scaffold: application to the synthesis of glucocorticoid receptor modulators. Hai-Yun Xiao et al J. Med. Chem. 53, 1270-80, (2010)

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Differential CD4+ T-lymphocyte apoptosis and bystander T-cell activation in rhesus macaques and sooty mangabeys during acute simian immunodeficiency virus infection. Meythaler M, Martinot A, Wang Z, et al. J. Virol. 83(2), 572-83, (2009)

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2-Amino-5-thiazolyl motif: a novel scaffold for designing anti-inflammatory agents of diverse structures. P X Franklin et al Eur. J. Med. Chem. 43, 129-34, (2008)

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Adrenal steroidogenesis following prenatal dexamethasone exposure in the spiny mouse. Quinn TA, Ratnayake U, Castillo-Melendez M, et al. J. Endocrinol. 221(2), 347-62, (2014)

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Synthesis and biological evaluation of a novel series of 2,2-bisaminomethylated aurone analogues as anti-inflammatory and antimicrobial agents. Babasaheb P Bandgar et al Eur. J. Med. Chem. 45, 3223-7, (2010)

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A predictive ligand-based Bayesian model for human drug-induced liver injury. Sean Ekins et al Drug Metab. Dispos. 38, 2302-8, (2010)

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Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-alpha and IL-6 inhibitors. Sandip B Bharate et al Bioorg. Med. Chem. 16, 7167-76, (2008)

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Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms. Jean Leandro dos Santos et al J. Med. Chem. 54, 5811-9, (2011)

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IFN-gamma reverses IL-2- and IL-4-mediated T-cell steroid resistance. Goleva E Am. J. Respir. Cell. Mol. Biol. 40(2), 223-30, (2009)

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Fabrication of a neotrachea using engineered cartilage. Weidenbecher M Laryngoscope 118(4), 593-8, (2008)

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Chisopanins A-K, 11 new protolimonoids from Chisocheton paniculatus and their anti-inflammatory activities. Ming-Hua Yang et al Bioorg. Med. Chem. 19, 1409-17, (2011)

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Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis. Tsutomu Akama et al Bioorg. Med. Chem. Lett. 19, 2129-32, (2009)

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Highly potent, orally available anti-inflammatory broad-spectrum chemokine inhibitors. David J Fox et al J. Med. Chem. 52, 3591-5, (2009)

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Dexamethasone modifies mitomycin C-triggered interleukin-8 secretion in isolated human Tenon's capsule fibroblasts. Ho WT, Chen TC, Chou SF, et al. Exp. Eye Res. 124, 86-92, (2014)

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Dexamethasone for acute asthma exacerbations in children: a meta-analysis. Keeney GE, Gray MP, Morrison AK, et al. Pediatrics 133(3), 493-9, (2014)

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The critical role of IL-34 in osteoclastogenesis. Zhi Chen et al PLoS ONE 6, e18689, (2011)

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Potential anti-inflammatory constituents of the stems of Gordonia chrysandra. Hui-Zheng Fu et al J. Nat. Prod. 74, 1066-72, (2011)

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Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice. Gutierrez GM Proc. Natl. Acad. Sci. U. S. A. 105(47), 18402-7, (2008)

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Determination of the fate and contribution of ex vivo expanded human bone marrow stem and progenitor cells for bone formation by 2.3ColGFP. Dezhong Yin et al Mol. Ther. 17, 1967-78, (2009)

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Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents. Babasaheb P Bandgar et al Bioorg. Med. Chem. 18, 2060-5, (2010)

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Three-year, randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with diabetic macular edema. Boyer DS, Yoon YH, Belfort R, et al. Ophthalmology 121(10), 1904-14, (2014)

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The lecanindoles, nonsteroidal progestins from the terrestrial fungus Verticillium lecanii 6144. Deborah M Roll et al J. Nat. Prod. 72, 1944-8, (2009)

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Activity of physalin F in a collagen-induced arthritis model. Daniele Brustolim et al J. Nat. Prod. 73, 1323-6, (2010)

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The Nup358-RanGAP complex is required for efficient importin α/β-dependent nuclear import. Saskia Hutten et al Mol. Biol. Cell 19, 2300-10, (2008)

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Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents. Roland W Bürli et al Bioorg. Med. Chem. Lett. 16, 3713-8, (2006)

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Synthesis and biological evaluation of beta-chloro vinyl chalcones as inhibitors of TNF-alpha and IL-6 with antimicrobial activity. Babasaheb P Bandgar et al Eur. J. Med. Chem. 45, 2629-33, (2010)

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Expression of caveolin in trabecular meshwork cells and its possible implication in pathogenesis of primary open angle glaucoma. Surgucheva I and Surguchov A Mol. Vis. 17, 2878-88, (2011)

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Transformation of isosteviol lactam by fungi and the suppressive effects of its transformed products on LPS-induced iNOS expression in macrophages. Bo-Hon Chou et al J. Nat. Prod. 74, 1379-85, (2011)

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Synthesis and biochemical characterization of a series of 17?-perfluoroalkylated estradiols as selective ligands for estrogen receptor ?. Barbara Eignerová et al J. Med. Chem. 53, 6947-53, (2010)

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Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus. Park BY and Saint-Jeannet JP Dev. Biol. 324(1), 108-21, (2008)

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Trifluoromethyl group as a pharmacophore: effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand. Raj Betageri et al Bioorg. Med. Chem. Lett. 15, 4761-9, (2005)

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Polymeric delivery systems for dexamethasone. Urbańska J, Karewicz A, and Nowakowska M Life Sci. 96(1-2), 1-6, (2014)

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Differentiating human multipotent mesenchymal stromal cells regulate microRNAs: prediction of microRNA regulation by PDGF during osteogenesis. Goff, LA Exp. Hematol. 36(10), 1354-1369, (2008)

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Glucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism. Liping Sun et al Proc. Natl. Acad. Sci. U. S. A. 105, 3339-44, (2008)

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Single high-dose dexamethasone and sodium salicylate failed to attenuate phosgene-induced acute lung injury in rats. Liu F, Pauluhn J, Trübel H, et al. Toxicology 315, 17-23, (2014)

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The novel 3,4-dihydropyrimidin-2(1H)-one urea derivatives of N-aryl urea: synthesis, anti-inflammatory, antibacterial and antifungal activity evaluation. Rajesh H Tale et al Bioorg. Med. Chem. Lett. 21, 4648-51, (2011)

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Constitutional flavonoids derived from Epimedium dose-dependently reduce incidence of steroid-associated osteonecrosis not via direct action by themselves on potential cellular targets. Zhang, G PLoS ONE 4(7), e6419, (2009)

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Mesenchymal stem cells improve wound healing in vivo via early activation of matrix metalloproteinase-9 and vascular endothelial growth factor. Kim CH J. Korean Med. Sci. 26(6), 726-33, (2011)

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IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone. Chen Y, Garvin LM, Nickola TJ, et al. Am. J. Physiol. Lung Cell. Mol. Physiol. 306(8), L797-807, (2014)

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Potent inhibitors of pro-inflammatory cytokine production produced by a marine-derived bacterium. Wendy K Strangman et al J. Med. Chem. 52, 2317-27, (2009)

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Transformation of steviol-16alpha,17-epoxide by Streptomyces griseus and Cunninghamella bainieri. Shwu-Fen Chang et al J. Nat. Prod. 69, 1450-5, (2006)

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Dexamethasone produces dose-dependent inhibition of sugammadex reversal in in vitro innervated primary human muscle cells. Rezonja K, Sostaric M, Vidmar G, et al. Anesth. Analg. 118(4), 755-63, (2014)

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Novel tricyclic compounds having acetylene groups at C-8a and cyano enones in rings A and C: highly potent anti-inflammatory and cytoprotective agents. Tadashi Honda et al J. Med. Chem. 50, 1731-4, (2007)

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Stringent complete remission of primary plasma cell leukemia with reduced-dose bortezomib, lenalidomide and dexamethasone: a case report and review of the literature. Ueda S, Kubo M, Matsuura N, et al. Intern. Med. 52(11), 1235-8, (2013)

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Corticosteroids found ineffective for phosgene-induced acute lung injury in rats. Luo S, Pauluhn J, Trübel H, et al. Toxicol. Lett. 229(1), 85-92, (2014)

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Structure Guided Design of 5-Arylindazole Glucocorticoid Receptor Agonists and Antagonists C. M. Yates, et al. J. Med. Chem. 53, 4531-4544, (2010)

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The α-subunit of the heterotrimeric G-protein affects jasmonate responses in Arabidopsis thaliana. Haruko Okamoto et al J. Exp. Bot. 60, 1991-2003, (2009)

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Identification of dissociated non-steroidal glucocorticoid receptor agonists. Daniel Kuzmich et al Bioorg. Med. Chem. Lett. 17, 5025-31, (2007)

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A pilot study in rhesus macaques to assess the treatment efficacy of a small molecular weight catalytic metalloporphyrin antioxidant (AEOL 10150) in mitigating radiation-induced lung damage. Garofalo MC, Ward AA, Farese AM, et al. Health Phys. 106(1), 73-83, (2014)

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Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Lei Du-Cuny et al Bioorg. Med. Chem. 17, 6983-92, (2009)

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Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats. Mann SA J. Neuroinflammation 5, 39, (2008)

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Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis. Olga Bruno et al J. Med. Chem. 50, 3618-26, (2007)

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Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application. Yong-Kang Zhang et al Bioorg. Med. Chem. Lett. 20, 2270-4, (2010)

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Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides. Bo Liu et al J. Med. Chem. 52, 4604-12, (2009)

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Effects of ?-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro. Liuqiang Zhang et al Bioorg. Med. Chem. 19, 4882-6, (2011)

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Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships. Shigeo Hayashi et al Bioorg. Med. Chem. 18, 7675-99, (2010)

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Does corticosteroid have any beneficial effect on voice change after thyroidectomy? Nasiri S, Shafag S, Khorgami Z, et al. Am. Surg. 79(12), 1258-62, (2013)

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Dynamic modulation of thymic microRNAs in response to stress. Serkan Belkaya et al PLoS ONE 6, e27580, (2011)

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Non-steroidal glucocorticoid agonists: the discovery of aryl pyrazoles as A-ring mimetics. Margaret Clackers et al Bioorg. Med. Chem. Lett. 17, 4737-45, (2007)

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Microbial transformation of isosteviol oxime and the inhibitory effects on NF-kappaB and AP-1 activation in LPS-stimulated macrophages. Shwu-Fen Chang et al Bioorg. Med. Chem. 17, 6348-53, (2009)

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Infection with Hymenolepis diminuta is more effective than daily corticosteroids in blocking chemically induced colitis in mice. Melon A J. Biomed. Biotechnol. 2010, 384523, (2010)

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Porcine glucocorticoid receptor (NR3C1) gene: tissue-specificity of transcriptional strength and glucocorticoid responsiveness of alternative promoters. Jiang Z, Qian L, Zou H, et al. J. Steroid Biochem. Mol. Biol. 141, 87-93, (2014)

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The delayed pulmonary syndrome following acute high-dose irradiation: a rhesus macaque model. Garofalo M, Bennett A, Farese AM, et al. Health Phys. 106(1), 56-72, (2014)

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Alkaloids from the Australian rainforest tree Ochrosia moorei. Anthony R Carroll et al J. Nat. Prod. 71, 1063-5, (2008)

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Combined antibacterial and anti-inflammatory activity of a cationic disubstituted dexamethasone-spermine conjugate. Robert Bucki et al Antimicrob. Agents Chemother. 54, 2525-33, (2010)

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Effectiveness of the association of dexamethasone with antibiotic therapy in pediatric patients with bacterial meningitis. Bernardo WM, Aires FT, and Sá FP Rev. Assoc. Med. Bras. 58(3), 319-22, (2012)

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Core exploration in optimization of chemokine receptor CCR4 antagonists. Ashok V Purandare et al Bioorg. Med. Chem. Lett. 17, 679-82, (2007)

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Syntheses of immunomodulating androstanes and stigmastanes: comparison of their TNF-alpha inhibitory activity. Javier A Ramírez et al Bioorg. Med. Chem. 15, 7538-44, (2007)

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Sundaicumones A and B, polyprenylated acylphloroglucinol derivatives from Calophyllumsundaicum with weak activity against the glucocorticoid receptor. Shugeng Cao et al J. Nat. Prod. 69, 707-9, (2006)

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Vision-related functioning outcomes of dexamethasone intravitreal implant in noninfectious intermediate or posterior uveitis. Lightman S, Belfort R, Naik RK, et al. Invest. Ophthalmol. Vis. Sci. 54(7), 4864-70, (2013)

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Discovery of novel dihydro-9,10-ethano-anthracene carboxamides as glucocorticoid receptor modulators. Bingwei V Yang et al Bioorg. Med. Chem. Lett. 19, 2139-43, (2009)

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Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold. Maurizio Aquino et al Bioorg. Med. Chem. 16, 9056-64, (2008)

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Antiinflammatory glucocorticoid receptor ligand with reduced side effects exhibits an altered protein-protein interaction profile. Jeffrey N Miner et al Proc. Natl. Acad. Sci. U. S. A. 104, 19244-9, (2007)

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Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models. Asaf A Qureshi et al Lipids Health Dis. 10, 177, (2011)

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Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes. Zhang Y Lipids Health Dis. 10, 122, (2011)

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Neural computational prediction of oral drug absorption based on CODES 2D descriptors. A Guerra et al Eur. J. Med. Chem. 45, 930-40, (2010)

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Alpha-lipoic acid attenuates adipocyte differentiation and lipid accumulation in 3T3-L1 cells via AMPK-dependent autophagy. Hahm JR, Noh HS, Ha JH, et al. Life Sci. 100(2), 125-32, (2014)

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Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response. Ihtzaz Ahmed Malik et al Cell Tissue Res. 344, 299-312, (2011)

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Cell cycle phase regulates glucocorticoid receptor function. Matthews L, Johnson J, Berry A, et al. PLoS ONE 6(7), e22289, (2011)

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QSAR-based permeability model for drug-like compounds. Rafael Gozalbes et al Bioorg. Med. Chem. 19, 2615-24, (2011)

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Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins. Alfonso Pérez-Garrido et al Bioorg. Med. Chem. 17, 896-904, (2009)

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Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores. Raj Betageri et al Bioorg. Med. Chem. Lett. 21, 6842-51, (2011)

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Dexamethasone-eluting vascular stents. Hämäläinen M, Nieminen R, Uurto I, et al. Basic Clin Pharmacol Toxicol. 112(5), 296-301, (2013)

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Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. Xiaofan Sui et al Eur. J. Med. Chem. 44, 4455-60, (2009)

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Role of dexamethasone in the prevention of migraine recurrence in the acute care setting: a review. Giuliano C, Smalligan RD, Mitchon G, et al. Postgrad. Med. 124(3), 110-5, (2012)

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Discovery of quinolines as selective glucocorticoid receptor agonists. Stefan Jaroch et al Bioorg. Med. Chem. Lett. 20, 5835-8, (2010)

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Early effects of dexamethasone and anti-VEGF therapy in an inflammatory corneal neovascularization model. Mirabelli P, Peebo BB, Xeroudaki M, et al. Exp. Eye Res. 125, 118-27, (2014)

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Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans. Nidhi Puri et al Eur. J. Med. Chem. 45, 4813-26, (2010)

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Dexamethasone intravitreal implant in the treatment of persistent uveitic macular edema in the absence of active inflammation. Cao JH, Mulvahill M, Zhang L, et al. Ophthalmology 121(10), 1871-6, (2014)

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T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival. Moro H, Otero DC, Tanabe Y, et al. PLoS ONE 6(9), e24972, (2011)

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Osteogenic abilities of bone marrow stromal cells are not defective in patients with osteonecrosis. Yoo JJ Int. Orthop. 33(3), 867-72, (2009)

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Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Yong-Hua Wang et al Bioorg. Med. Chem. Lett. 15, 4076-84, (2005)

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Dexamethasone, but not meloxicam, suppresses proliferation of bovine CD25+ CD4+ and CD25- CD4+ T cells. Maślanka T and Jaroszewski JJ Pol. J. Vet. Sci. 16(2), 219-22, (2013)

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α-Methyltryptamine sulfonamide derivatives as novel glucocorticoid receptor ligands Marshall, D. R.; et al. Bioorg. Med. Chem. Lett. 17, 315, (2007)

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Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity. Cha JY, Kim HJ, Yu JH, et al. Proc. Natl. Acad. Sci. U. S. A. 110(51), 20575-80, (2013)

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Mast cells prevent dexamethasone-induced cell death of cultured fibroblasts: relationship to gap junctional intercellular communications. Foley TT and Ehrlich HP Plast. Reconstr. Surg. 133(5), 638e-644e, (2014)

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Long-term dexamethasone treatment alters the histomorphology of acinar cells in rat parotid and submandibular glands. Bighetti BB, d Assis GF, Vieira DC, et al. Int. J. Exp. Pathol. 95(5), 351-63, (2014)

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Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. Elisa Giner et al J. Nat. Prod. 74, 1079-84, (2011)

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Trimethylsilylpyrazoles as novel inhibitors of p38 MAP kinase: a new use of silicon bioisosteres in medicinal chemistry. Matthew J Barnes et al Bioorg. Med. Chem. Lett. 17, 354-7, (2007)

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Effectiveness of gemcitabine, pegaspargase, cisplatin, and dexamethasone (DDGP) combination chemotherapy in the treatment of relapsed/refractory extranodal NK/T cell lymphoma: a retrospective study of 17 patients. Zhou Z, Li X, Chen C, et al. Ann. Hematol. 93(11), 1889-94, (2014)

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6-amino-4-oxo-1,3-diphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl derivatives as a new class of potent inhibitors of Interleukin-8-induced neutrophil chemotaxis. Sara Cesarini et al Bioorg. Med. Chem. 17, 3580-7, (2009)

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1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors. Olga Bruno et al Bioorg. Med. Chem. 17, 3379-87, (2009)

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Tetrahydroquinolines as a novel series of nonsteroidal selective androgen receptor modulators: structural requirements for better physicochemical and biological properties. Naoya Nagata et al Bioorg. Med. Chem. Lett. 21, 6310-3, (2011)

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5-Functionalized indazoles as glucocorticoid receptor agonists. Mei Bai et al Bioorg. Med. Chem. Lett. 20, 3017-20, (2010)

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Synthesis and biological evaluation of nitrogen-containing benzophenone analogues as TNF-alpha and IL-6 inhibitors with antioxidant activity. Babasaheb P Bandgar et al Bioorg. Med. Chem. Lett. 20, 2292-6, (2010)

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Stability and removal of dexamethasone sodium phosphate from wastewater using modified clays. Sulaimana S, Khamis M, Nir S, et al. Environ. Technol. 35(13-16), 1945-55, (2014)

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Mesenchymal stromal cell proliferation, gene expression and protein production in human platelet-rich plasma-supplemented media. Amable PR, Teixeira MV, Carias RB, et al. PLoS ONE 9(8), e104662, (2014)

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Haploinsufficiency of Def activates p53-dependent TGFβ signalling and causes scar formation after partial hepatectomy. Zhu Z, Chen J, Xiong JW, et al. PLoS ONE 9(5), e96576, (2014)

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Mapracorat, a selective glucocorticoid receptor agonist, upregulates RelB, an anti-inflammatory nuclear factor-kappaB protein, in human ocular cells. Spinelli SL, Xi X, McMillan DH, et al. Exp. Eye Res. 127, 290-8, (2014)

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Treatment outcome in children and adolescents with relapsed Hodgkin lymphoma--results of the UK HD3 relapse treatment strategy. Shankar A, Hayward J, Kirkwood A, et al. Br. J. Haematol. 165(4), 534-44, (2014)

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Cutting edge: Dexamethasone potentiates the responses of both regulatory T cells and B-1 cells to antigen immunization in the ApoE(-/-) mouse model of atherosclerosis. Chen A, Geng Y, Ke H, et al. J. Immunol. 193(1), 35-9, (2014)

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[Hyperammonemic encephalopathy in multiple myeloma]. Oestmann A and Aujesky D Dtsch. Med. Wochenschr. 139(30), 1518-20, (2014)

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Low-dose oral mini-pulse dexamethasone therapy in progressive unstable vitiligo. Kanwar AJ, Mahajan R, and Parsad D J. Cutan. Med. Surg. 17(4), 259-68, (2013)

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Design and synthesis of tricyclic tetrahydroquinolines as a new series of nonsteroidal selective androgen receptor modulators (SARMs). Naoya Nagata et al Bioorg. Med. Chem. Lett. 21, 1744-7, (2011)

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A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Myers RM, Balsamo L, Lu X, et al. Cancer 120(9), 1417-25, (2014)

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Androgen resistance in squirrel monkeys (Saimiri spp.). Gross KL Comp. Med. 58(4), 381-8, (2008)

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Modulation of glucocorticoid receptor induction properties by cofactors in peripheral blood mononuclear cells. Luo M and Simons SS Hum. Immunol. 70(10), 785-9, (2009)

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Analysis of gene expression for studying tumor progression: the case of glucocorticoid administration. Huerta M, Fernández-Márquez J, Cabello JL, et al. Gene 549(1), 33-40, (2014)

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Highly tractable, sub-nanomolar non-steroidal glucocorticoid receptor agonists. Keith Biggadike et al Bioorg. Med. Chem. Lett. 19, 4846-50, (2009)

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Inhibition of COX-1 activity and COX-2 expression by 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its semi-synthetic derivatives. Salvatore Genovese et al Bioorg. Med. Chem. Lett. 21, 5995-8, (2011)

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Discovery of a potent series of non-steroidal non ?-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicity. Hawa Diallo et al Bioorg. Med. Chem. Lett. 21, 1126-33, (2011)

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Ciprofloxacin 0.3% + dexamethasone 0.1% for the treatment for otitis media. Kutz JW, Roland PS, and Lee KH Expert Opin. Pharmacother. 14(17), 2399-405, (2013)

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Acute ablation of DP thymocytes induces up-regulation of IL-22 and Foxn1 in TECs. Pan B, Liu J, Zhang Y, et al. Clin. Immunol. 150(1), 101-8, (2014)

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Modulation of Human Serotonin Transporter Expression by 5-HTTLPR in Colon Cells. Prasansuklab A, Poovorawan Y, and Tencomnao T Int. J. Mol. Sci. 12(10), 6619-34, (2011)

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Microwave-enhanced nucleophilic fluorination in the synthesis of fluoropyridyl derivatives of [3,2-c]pyrazolo-corticosteroids, potential glucocorticoid receptor-mediated imaging agents. Michael G C Kahn et al Bioorg. Med. Chem. Lett. 16, 3454-8, (2006)

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Rituximab-cyclophosphamide-dexamethasone is highly effective in patients with monoclonal Ig deposit-related glomerulopathy and indolent non-Hodgkin lymphomas. Perry M, Delarche A, Ribes D, et al. Am. J. Hematol. 89(10), 969-73, (2014)

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Dexamethasone effects on vascular flow and organ injury in septic mice. Aytac HO, Iskit AB, and Sayek I J. Surg. Res. 188(2), 496-502, (2014)

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Dexamethasone plus somatostatin-analog manipulation as bone metastasis microenvironment-targeting therapy for the treatment of castration-resistant prostate cancer: a meta-analysis of uncontrolled studies. Toulis KA, Goulis DG, Msaouel P, et al. Anticancer Res. 32(8), 3283-9, (2012)

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Comparison of clinical effects of prilocaine, dexamethasone added to prilocaine and levobupivacaine on brachial plexus block. Saritas A and Sabuncu C J. Pak. Med. Assoc. 64(4), 433-6, (2014)

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Acute migraine treatment in emergency settings. Saguil A and Lax JW Am. Fam. Physician 89(9), 742-4, (2014)

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A syndecan-4 binding peptide derived from laminin 5 uses a novel PKCε pathway to induce cross-linked actin network (CLAN) formation in human trabecular meshwork (HTM) cells. Filla MS, Clark R, and Peters DM Exp. Cell Res. 327(2), 171-82, (2014)

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Relative adrenal insufficiency in mice deficient in 5α-reductase 1. Livingstone DE, Di Rollo EM, Yang C, et al. J. Endocrinol. 222(2), 257-66, (2014)

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Changes in macular function after ozurdex for retinal vein occlusion. Querques G, Cascavilla ML, Cavallero E, et al. Optom. Vis. Sci. 91(7), 760-8, (2014)

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Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. Pil H Lee et al Bioorg. Med. Chem. Lett. 20, 69-73, (2010)

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Mammalian nitrilase 1 homologue Nit1 is a negative regulator in T cells. Zhang H Int. Immunol. 21(6), 691-703, (2009)

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Improvement of adherence to guidelines for antiemetic medication enhances emetic control in patients with colorectal cancer receiving chemotherapy of moderate emetic risk. Fujii H, Iihara H, Ishihara M, et al. Anticancer Res. 33(12), 5549-56, (2013)

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A new technique of bronchial microsampling and proteomic analysis of epithelial lining fluid in a rat model of acute lung injury. Kamiyama I, Kohno M, Kamiya K, et al. Mol. Immunol. 59(2), 217-25, (2014)

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Neuronal Fos-like immunoreactivity associated with dexamethasone-induced hypertension in rats and effects of glucagon-like peptide-2. Sasaki-Hamada S, Ito K, and Oka J Life Sci. 93(23), 889-96, (2013)

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Is a dexamethasone-sparing strategy capable of preventing acute and delayed emesis caused by combined doxorubicin and paclitaxel for breast cancer? Analysis of a phase II trial. Damian S, Celio L, De Benedictis E, et al. Oncology 84(6), 371-7, (2013)

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Choice of glucocorticoid in HELLP syndrome - dexamethasone versus betamethasone: revisiting the dilemma. Basaran A, Basaran M, and Sen C J. Matern. Fetal. Neonatal. Med. 25(12), 2597-600, (2012)

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The research on the immuno-modulatory defect of mesenchymal stem cell from Chronic Myeloid Leukemia patients. Zhu Xishan et al J. Exp. Clin. Cancer Res 30, 47, (2011)

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Congenital nasal pyriform aperture stenosis: conservative management. Collins B, Powitzky R, Enix J, et al. Ann. Otol. Rhinol. Laryngol. 122(10), 601-4, (2013)

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Efficacy of dexamethasone in the prophylaxis of nausea and vomiting during the postoperative period of laparoscopic cholecystectomy. Bernardo WM and Aires FT Rev. Assoc. Med. Bras. 59(4), 387-91, (2013)

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Identification of functional glucocorticoid response elements in the mouse FoxO1 promoter. Qin W, Pan J, Qin Y, et al. Biochem. Biophys. Res. Commun. 450(2), 979-83, (2014)

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A retrospective study of acute mountain sickness on Mt. Kilimanjaro using trekking company data. Eigenberger P, Faino A, Maltzahn J, et al. Aviat. Space. Environ. Med. 85(11), 1125-9, (2014)

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Post-transplantation consolidation and maintenance therapy with lenalidomide for Japanese patients with multiple myeloma. Takamatsu H, Munemoto S, Murata R, et al. Anticancer Res. 33(12), 5681-5, (2013)

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Von Willebrand Factor and Factor VIII levels in Egyptian children with newly diagnosed acute lymphoblastic leukemia in relation to peripheral blast cells and steroid therapy. El Sherif NH, Narouz MF, Elkerdany TA, et al. J. Pediatr. Hematol. Oncol. 36(7), 518-23, (2014)

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Clinical outcomes of AIDS-related Burkitt lymphoma: a multi-institution retrospective survey in Japan. Kojima Y, Hagiwara S, Uehira T, et al. Jpn. J. Clin. Oncol. 44(4), 318-23, (2014)

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Antemortem diagnosis and successful management of noncompressive segmental myelopathy in a Siberian-Bengal mixed breed tiger. Flower JE, Lynch K, Clark-Price SC, et al. J. Zoo Wildl. Med. 44(4), 1115-9, (2013)

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MIF attenuates the suppressive effect of dexamethasone on IL-6 production by nasal polyp. Stathas T, Athanassiou SD, Drakouli S, et al. Eur. Rev. Med. Pharmacol. Sci. 17(11), 1455-66, (2013)

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The effects of dexamethasone and metoclopramide on early and late postoperative nausea and vomiting in women undergoing myomectomy under spinal anaesthesia. Tobi KU, Imarengiaye CO, and Amadasun FE Niger. J. Clin. Pract. 17(4), 449-55, (2014)

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Impaired gonadal function in a woman with multiple symmetric lipomatosis. Rendina D, De Filippo G, Nazzaro A, et al. Minerva Endocrinol. 38(2), 211-5, (2013)

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Hypoglycaemic effects of alcoholic root extract of Borassus flabellifer (Linn.) in normal and diabetic rats. Debnath T, Radhakrishnan R, Murugananthan G, et al. Pak. J. Pharm. Sci. 26(4), 673-9, (2013)

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Effect of intravenous dexamethasone on prevertebral soft tissue swelling after anterior cervical discectomy and fusion. Nam TW, Lee DH, Shin JK, et al. Acta Orthop. Belg. 79(2), 211-5, (2013)

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POEMS syndrome: a challenging diagnosis of a rare disease. Creamer A, Gaastra B, Odogwu S, et al. Br. J. Hosp. Med. (Lond.) 75(7), 408-9, (2014)

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Current treatment for multiple myeloma. Avigan D and Rosenblatt J N. Engl. J. Med. 371(10), 961-2, (2014)

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Author reply: To PMID 24246828. Afshar AR and Stewart JM Ophthalmology 121(10), e57, (2014)

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Re: Afshar et al.: Dexamethasone intravitreal implant trapped at the macula in a silicone oil-filled eye (Ophthalmology 2013;120:2748-9). Banerjee PJ, Petrou P, and Charteris DG Ophthalmology 121(10), e55-7, (2014)

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Aprepitant versus dexamethasone to prevent delayed emesis after chemotherapy. Ng TL, Clemons M, Hutton B, et al. J. Clin. Oncol. 32(20), 2184-5, (2014)

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Reply to T.L. Ng et al and L. Celio et al. Roila F, Fatigoni S, and Ballatori E J. Clin. Oncol. 32(20), 2187-8, (2014)

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Aprepitant versus dexamethasone for delayed emesis: what is the role of the 5-hydroxytryptamine type 3 receptor antagonist palonosetron? Celio L, de Braud F, and Aapro M J. Clin. Oncol. 32(20), 2185-6, (2014)

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Perineural dexamethasone and multimodal perineural analgesia: how much is too much? Williams BA, Schott NJ, Mangione MP, et al. Anesth. Analg. 118(5), 912-4, (2014)

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Long-term plasmapheresis in conjunction with thalidomide and dexamethasone for the treatment of cutaneous ulcers and neovascular glaucoma in recalcitrant type I cryoglobulinemia. Yang CH, Qureshi AA, Churchill WH, et al. JAMA Dermatol. 150(4), 426-8, (2014)

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Stopping the swinging pendulum of postnatal corticosteroid use. Demauro SB, Dysart K, and Kirpalani H J. Pediatr. 164(1), 9-11, (2014)

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Hyperkalemia: a clue to the diagnosis of adrenal insufficiency. El Fassi D and Nielsen G Circulation 128(24), 2620-1, (2013)

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Dexamethasone for increasing analgesic duration of single-shot inter-scalene block. Fields KG and YaDeau J Br. J. Anaesth. 112(1), 176-7, (2014)

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Intravenous or perineural dexamethasone for interscalene brachial plexus block: the equivalence not yet proven. Sondekoppam RV, Uppal V, and Ganapathy S Br. J. Anaesth. 112(1), 175-6, (2014)

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Is no nausea worth a little insulin? Allen GC Br. J. Anaesth. 112(1), 172, (2014)

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Question 1: Prednisolone or dexamethasone for acute exacerbations of asthma: do they have similar efficacy in the management of exacerbations of childhood asthma? Redman E and Powell C Arch. Dis. Child. 98(11), 916-9, (2013)

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Light chain deposition. Hsia CC and Chan NG Blood 121(26), 5111, (2013)

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Stopping trials early. Myles PS Br. J. Anaesth. 111(2), 133-5, (2013)

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Preoperative use of steroids in pediatric cardiac surgery: new directions for future research? Vitale V, Ricci Z, and Cogo P Ann. Thorac. Surg. 96(1), 375, (2013)

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Clinically relevant genetic advances in endocrinology. Rogers A and Thakker RV Clin. Med. 13(3), 299-305, (2013)

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A novel mechanism for glucocorticoid-induced tightening of endothelial barriers. Duh EJ Invest. Ophthalmol. Vis. Sci. 54(6), 4016, (2013)

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Response to: "Possible errors in hearing recovery results" from Kai-Min Fang. Lim HJ, Kim YT, Park HY, et al. Otolaryngol. Head Neck Surg. 148(6), 1063, (2013)

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Possible errors in hearing recovery results. Sung PH and Fang KM Otolaryngol. Head Neck Surg. 148(6), 1062, (2013)

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Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 2: Dexamethasone for reduction of migraine recurrence. Neill A and Brannigan D Emerg. Med. J. 30(2), 165-6, (2013)

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Merck 14,2943

Aldrich MSDS 1, 556:D / Corp MSDS 1 (1), 1039:B / FT-NMR 1 (3), 585:C / RegBook 1 (2), 2863:L / Sax 6, 2493 / Sigma FT-IR 1 (1), 1233:A / Structure Index 1, 458:A:8

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