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D5670 Sigma

Sodium deoxycholate monohydrate

BioXtra, ≥99.0% (titration)

Synonym: 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

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Properties

Related Categories Anionic Detergents, Antigen-Vaccine Preparation, Bile Salts, Biochemicals and Reagents, Cell Culture,
description   anionic
InChI Key   NDVHNZISGVSFMP-WTCAICSISA-M
product line   BioXtra
assay   ≥99.0% (titration)
optical activity   [α]20/D +44±2° in H2O(lit.)
impurities   Insoluble matter, passes filter test
  ≤0.5% Cholic acid
pH   7.5-9.5 (20 °C, 0.1 M in H2O)
solubility   H2O: soluble0.1 M, clear, colorless
anion traces   sulfate (SO42-): ≤0.02%
cation traces   Al: ≤0.002%
  Ba: ≤0.0005%
  Bi: ≤0.0005%
  Ca: ≤0.05%
  Cd: ≤0.0005%
  Co: ≤0.0005%
  Cr: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.001%
  K: ≤0.010%
  Li: ≤0.0005%
  Mg: ≤0.002%
  Mn: ≤0.0005%
  Mo: ≤0.0005%
  Ni: ≤0.0005%
  Pb: ≤0.0005%
  Sr: ≤0.002%
  Zn: ≤0.0005%
absorption   A0.1M/260, H2O ≤0.10
  A0.1M/280, H2O ≤0.08

Description

Application

Powerful solubilization agent; used in the solubilization of estrogen synthetase from human placental microsomes.

Sodium deoxycholate monohydrate has been used in a study to assess a method for the immobilization of lipoxygenase in an alginate-silicate gel matrix. It has also been used in a study to investigate the in vitro dissolution of gall stones.

Biochem/physiol Actions

Bile Salt

Packaging

5, 25 g in poly bottle

General description

Sodium deoxycholate (SDC) monohydrate is a bile acid salt.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, Transcription

Bile Salts and Bile Salt Hydrolase

Several Lactobacillus and Bifidobacterium probiotic strains exhibit bile salt hydrolase (BSH) activity and are suspected to play a role in combating the negative effects of bile via detoxification of...
Chloe McClanahan
Biofiles Edition 6.2
Keywords: Detoxification, Probiotics, Thin layer chromatography, Titrations

Probiotics and Human Health

At the beginning of the 20th century, probiotics were thought to have a beneficial effect to the host by improving the intestinal microbial balance. Through his studies and observations, the Russian ...
Chloe McClanahan
BioFiles Edition 6.2
Keywords: AGE, Absorption, Adhesion, Amplification, Anaerobic, Antimicrobials, Apoptosis, Cancer, Capillary electrophoresis, Carcinogens, Cell culture, Cell proliferation, Chromatography, Coagulation, Detoxification, Diagnostic, Diseases, Enzyme activity, Fermentation, Gas chromatography, Gastrointestinal, Genomics, High performance liquid chromatography, Immunology, Inflammation, Magnetic resonance spectroscopy, Metabolism, Metabolites, Microbiology, Molecular biology, Nucleic acid hybridization, Pharmaceutical, Phosphorylations, Polymerase chain reaction, Polymerase chain reaction - quantitative, Prebiotics, Probiotics, Reductions, Respiratory, Sequencing, Thin layer chromatography, Titrations

Peer-Reviewed Papers
15

References

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