Diclofenac sodium salt

Papers

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Giulia Caron et al J. Med. Chem. 48, 3269-79, (2005)

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Synthesis and biological evaluation of novel angularly fused polycyclic coumarins. Imtyaz A Khan et al Bioorg. Med. Chem. Lett. 15, 3584-7, (2005)

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Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents. Stanislav Gobec et al Bioorg. Med. Chem. Lett. 15, 5170-5, (2005)

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Design and synthesis of new water-soluble tetrazolide derivatives of celecoxib and rofecoxib as selective cyclooxygenase-2 (COX-2) inhibitors. Latifeh Navidpour et al Bioorg. Med. Chem. Lett. 16, 4483-7, (2006)

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Diclofenac solubility: independent determination of the intrinsic solubility of three crystal forms. Antonio Llinàs et al J. Med. Chem. 50, 979-83, (2007)

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Synthesis and biological evaluation of some 5-ethoxycarbonyl-6-isopropylamino-4-(substitutedphenyl)aminopyrimidines as potent analgesic and anti-inflammatory agents. Mahesh T Chhabria et al Bioorg. Med. Chem. Lett. 17, 1022-4, (2007)

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Synthesis of some bioactive 2-bromo-5-methoxy-N'-[4-(aryl)-1,3-thiazol-2-yl]benzohydrazide derivatives. K K Vijaya Raj et al Eur. J. Med. Chem. 42, 425-9, (2007)

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Studies on synthesis and pharmacological activities of 3,6-disubstituted-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and their dihydro analogues. Vinod Mathew et al Eur. J. Med. Chem. 42, 823-40, (2007)

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Chemical genetics reveals a complex functional ground state of neural stem cells Diamandis, P., et. al. Nat. Chem. Biol. 3(5), 268-273, (2007)

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Design, synthesis and evaluation of antiinflammatory, analgesic and ulcerogenicity studies of novel S-substituted phenacyl-1,3,4-oxadiazole-2-thiol and Schiff bases of diclofenac acid as nonulcerogenic derivatives. Shashikant V Bhandari et al Bioorg. Med. Chem. 16, 1822-31, (2008)

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Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening. Mojca Brunskole et al Bioorg. Med. Chem. 16, 5881-9, (2008)

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Synthesis of 4-substituted pyrido[2,3-d]pyrimidin-4(1H)-one as analgesic and anti-inflammatory agents. Abdel-Rahman B A El-Gazzar et al Bioorg. Med. Chem. Lett. 19, 3392-7, (2009)

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Synthesis, biological evaluation and docking studies of novel benzopyranone congeners for their expected activity as anti-inflammatory, analgesic and antipyretic agents. Amal A M Eissa et al Bioorg. Med. Chem. 17, 5059-70, (2009)

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Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents. Sherif A F Rostom et al Bioorg. Med. Chem. 17, 882-95, (2009)

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Design and synthesis of azolopyrimidoquinolines, pyrimidoquinazolines as anti-oxidant, anti-inflammatory and analgesic activities. A B A El-Gazzar et al Eur. J. Med. Chem. 44, 609-24, (2009)

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Synthesis, analgesic and anti-inflammatory activities of novel 3-(4-acetamido-benzyl)-5-substituted-1,2,4-oxadiazoles. Mazahar Farooqui et al Eur. J. Med. Chem. 44, 794-9, (2009)

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Identification and characterization of mefloquine efficacy against JC virus in vitro. Margot Brickelmaier et al Antimicrob. Agents Chemother. 53, 1840-9, (2009)

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Synthesis, analgesic and anti-inflammatory activities of some novel pyrazolines derivatives. Ratnadeep S Joshi et al Bioorg. Med. Chem. Lett. 20, 3721-5, (2010)

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Synthesis and anti-inflammatory activity of novel (substituted)benzylidene acetone oxime ether derivatives: molecular modeling study. Mohammed I El-Gamal et al Eur. J. Med. Chem. 45, 1403-14, (2010)

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Synthesis of some new pyrimido[2',1':2,3]thiazolo[4,5-b]quinoxaline derivatives as anti-inflammatory and analgesic agents. A A Abu-Hashem et al Eur. J. Med. Chem. 45, 1976-81, (2010)

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Synthesis, anti-inflammatory and ulcerogenicity studies of some substituted pyrimido[1,6-a]azepine derivatives. Nehad A El-Sayed et al Eur. J. Med. Chem. 45, 3147-54, (2010)

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Synthesis and pharmacological study of 1-acetyl/propyl-3-aryl-5-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-pyrazoline. K S Girisha et al Eur. J. Med. Chem. 45, 4640-4, (2010)

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Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether. Shelly Sharma et al Eur. J. Med. Chem. 45, 5150-6, (2010)

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Synthesis and biological evaluation of some 1,3,4-oxadiazole derivatives. K Manjunatha et al Eur. J. Med. Chem. 45, 5225-33, (2010)

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Synthesis, characterization and biological activities of some new benzo[b]thiophene derivatives. Arun M Isloor et al Eur. J. Med. Chem. 45, 825-30, (2010)

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Synthesis, characterization, and biological evaluation of novel diclofenac prodrugs. Babasaheb P Bandgar et al J. Med. Chem. 54, 1202-10, (2011)

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Synthesis and anti-inflammatory activity of some new 4,5-dihydro-1,5-diaryl-1H-pyrazole-3-substituted-heteroazole derivatives. Deepak V Dekhane et al Bioorg. Med. Chem. Lett. 21, 6527-32, (2011)

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A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin. Sungwook Choi et al Bioorg. Med. Chem. 19, 1505-14, (2011)

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Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study. Magda A-A El-Sayed et al Bioorg. Med. Chem. 19, 3416-24, (2011)

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Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. B Ramesh et al Eur. J. Med. Chem. 46, 1882-91, (2011)

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Design, synthesis, computational and biological evaluation of some new hydrazino derivatives of DHA and pyranopyrazoles. Ajay Kumar et al Eur. J. Med. Chem. 50, 81-9, (2012)

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Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat. Kobayashi, K., et al. Biochem. Pharmacol. 63, 889-896, (2002)

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Kirchheiner, J., et al. Br. J. Pharmacol. 55, 51-61, (2003)

Merck 14,3081