Demecolcine
≥98% (HPLC)
DOWNLOAD MSDS (PDF)Synonym:
N-
-
CAS Number 477-30-5
-
Empirical Formula (Hill Notation) C21H25NO5
-
Molecular Weight 371.43
-
Beilstein Registry Number 2822892
-
EC Number 207-514-6
-
MDL number MFCD00075459
-
PubChem Substance ID 24894128
-
Popular Documents: FTNMR (PDF)
Properties
| Related Categories | Apoptosis and Cell Cycle, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytoskeleton and Extracellular Matrix, |
| assay | ≥98% (HPLC) |
| solubility | chloroform: soluble10 mg/mL |
| ethanol: soluble | |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
Depolymerizes microtubules; blocks mitosis at metaphase.
Often in karyotyping and cell cycle research it is desirable to increase the yield of mitotic cells in a particular phase of the cell cycle. This can be achieved in a variety of ways with the most popular being the use of a cell cycle synchronizing agent such as demecolcine. Demecolcine will arrest cells in metaphase with no remarkable effect on the biochemical events in mitotic cells or in synchronized G1 and S phase cells. White blood cells are often treated with demecolcine to arrest cells in metaphase.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Price and Availability
Customers Also Viewed
Related Papers
Technical Service:
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Bulk Ordering & Pricing:
Need larger quantities for your development, manufacturing or research applications?
