CAS Number 9011-18-1
MDL number MFCD00081551
Popular Documents: Product Information Sheet (PDF) | Specification Sheet (PDF)
| Related Categories | Biochemicals, Biochemicals and Reagents, Blocking Reagents for Hybridization, Carbohydrate adjuvants, Carbohydrates, |
| Quality Level | PREMIUM |
| grade | for molecular biology |
| form | powder |
| mol wt | average Mw >500,000 (dextran starting material) |
| contains | 0.5-2% phosphate buffer |
| solubility | H2O: soluble100 mg/mL |
| storage temp. | 2-8°C |
Dextran sulfate has many applications and when performing nucleic acid hybridizations, may be used as an accelerant to decrease the time required for probe annealing. Dextran sulfate may be included in the hybridization buffer when the rate of hybridization is a limiting factor in detecting rare sequences or it may be included in the hybridization buffer when a limited amount of probe is available. Dextran sulfate functions as an accelerant by excluding the nucleic acid from the volume of solution occupied by the polymer, thereby, increasing the effective probe concentration.
Tested for suitability in nucleic acid hybridizations
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Mr ~40,000
average mol wt 5,000
mol wt 6,500-10,000
average mol wt 9,000-20,000
average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8
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