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E0518 Sigma

C1 Esterase Inhibitor from human plasma

aqueous solution, ≥95% (SDS-PAGE)

Synonym: Complement C1 esterase inhibitor, Esterase inhibitor C-1 from human plasma

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Description

Physical form

Solution in 20 mM potassium phosphate, pH 7.0, containing 250 mM KCl

Biochem/physiol Actions

Esterase inhibitor C1 is a multifunctional regulator of all major kinin-generating protein cascade systems. It has been a therapeutic tool in the treatment of hereditary angioedema and complement-mediated inflammatory tissue damage such as capillary leak syndrome, septic shock, multiple organ failure, and hyperacute graft rejection.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

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