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E0653 Sigma

Ephrin-B1/Fc Chimera from mouse

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym: Cek5-L, EFL-3, ELK-L, LERK-2, STRA-1

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Properties

Related Categories Angiogenesis, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors,
recombinant   expressed in NSO cells
assay   >95% (SDS-PAGE)
form   lyophilized powder
mol wt   monomer calculated mol wt 49.2 kDa
  mol wt ~60 kDa by SDS-PAGE (reducing)
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   mouse ... Efnb1(13641)

Description

Analysis Note

The biological activity is measured by its ability to bind recombinant mouse EphB3/Fc in ELISA.

Biochem/physiol Actions

Member of the ephrin ligand family that binds Eph receptor tyrosine kinases (EphA3, EphB1, EphB2, EphB3, and EphB4). Involved in pattern formation and morphogenesis. Ephrin-B1 is involved in integrin-mediated endothelial cell migration and attachment.

General description

Extracellular domain of mouse ephrin-B1 (amino acids 1-229) is fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
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