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E0778 Sigma

Ephrin-B2/Fc Chimera from mouse

>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym: ELF-2, Htk-L, LERK-5, NLERK-1

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Properties

Related Categories Angiogenesis, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors,
recombinant   expressed in NSO cells
assay   >90% (SDS-PAGE)
form   lyophilized powder
mol wt   monomer calculated mol wt 49.6 kDa
  mol wt 60-65 kDa by SDS-PAGE (reducing)
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   mouse ... Efnb2(13642)

Description

Analysis Note

The biological activity is measured by its ability to bind immobilized recombinant mouse EphB2/Fc in ELISA.

Biochem/physiol Actions

Member of ephrin ligand family that binds Eph receptor tyrosine kinases (EphA4, EphB1, EphB2, EphB3, and EphB4). Involved in pattern formation and morphogenesis. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cells.

Other Notes

Extracellular domain of mouse ephrin-B2 (amino acids 1-227) fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
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