Estriol ≥97% | Sigma-Aldrich

Properties

Related Categories	Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, E, Estrogen, Hormones, Nutrition Research, Phytochemicals by Chemical Classification, Steroid, Steroid Hormones More...
assay	≥97%
mp	280-282 °C(lit.)
Gene Information	human ... SERPINA6(866) mouse ... Esr1(13982) rat ... Ar(24208)

Description

Biochem/physiol Actions

Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and estrone are produced by the placenta during pregnancy. These are also the primary estrogens produced by adipose tissue in men and in post-menopausal women.

Packaging

1 g in poly bottle

100, 500 mg in poly bottle

Price and Availability

Related Papers

Regulation of estrogen biosynthesis by human adipose cells in vitro. Mendelson, C.R. Mol. Cell. Endocrinol. 52, 169, (1987)

Documents

Certificate of Analysis

Certificate of Origin

FT-IR Raman

FT-NMR

Safety Information

Symbol	GHS08
Signal word	Danger
Hazard statements	H351-H360
Precautionary statements	P201-P281-P308 + P313
Personal Protective Equipment	Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes (Europe)	T
Risk Statements (Europe)	60-61-40
Safety Statements (Europe)	53-36/37-45
WGK Germany	3
RTECS	KG8225000

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Papers

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Regulation of estrogen biosynthesis by human adipose cells in vitro. Mendelson, C.R. Mol. Cell. Endocrinol. 52, 169, (1987)

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Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Giulia Caron et al J. Med. Chem. 48, 3269-79, (2005)

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Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Markus A Lill et al J. Med. Chem. 48, 5666-74, (2005)

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Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bram Baert et al Bioorg. Med. Chem. 15, 6943-55, (2007)

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Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography. Larissa M Podust et al Antimicrob. Agents Chemother. 51, 3915-23, (2007)

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An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. Artem Cherkasov et al J. Med. Chem. 51, 2047-56, (2008)

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Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Edith Bellavance et al J. Med. Chem. 52, 7488-502, (2009)

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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Denis Fourches et al Chem. Res. Toxicol. 23, 171-83, (2010)

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Merck 14,3707

Beil. 6,IV,7550

Corp MSDS 1 (1), 1539:D / FT-IR 2 (3), 4218:D / FT-NMR 1 (3), 565:C / RegBook 1 (2), 2853:N / Sigma FT-IR 1 (1), 1247:C / Structure Index 1, 457:B:3