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E125 Sigma

β-Estradiol

Synonym: 1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin

  • CAS Number 50-28-2

  • Empirical Formula (Hill Notation) C18H24O2

  • Molecular Weight 272.38

  •  Beilstein Registry Number 1914275

  •  EC Number 200-023-8

  •  MDL number MFCD00003693

  • Popular Documents:  FTNMR (PDF)  

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Properties

InChI Key   VOXZDWNPVJITMN-ZBRFXRBCSA-N
mp   176-180 °C(lit.)
storage temp.   2-8°C

Description

Biochem/physiol Actions

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.

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Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
KG2975000
Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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E8875 β-Estradiol, ≥98%

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