EMAIL THIS PAGE TO A FRIEND

E1383 Sigma

Etoposide

synthetic, ≥98%, powder

Synonym: 4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside), VP-16-213

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Biochem/physiol Actions

Etoposide is an antitumor agent that complexes with topoisomerase II and DNA to enhance double-strand and single-strand cleavage of DNA and reversibly inhibit religation. Blocks the cell cycle in in S-phase and G2-phase of the cell cycle; induces apoptosis in normal and tumor cell lines; inhibits synthesis of the oncoprotein Mdm2 and induces apoptosis in tumor lines that overexpress Mdm2.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®,1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Additional Products to Explore

(<I>S</I>)-(+)-Camptothecin

≥90% (HPLC), powder

5-Fluorouracil

≥99% (HPLC), powder

Doxorubicin hydrochloride

98.0-102.0% (HPLC)

Paclitaxel

from Taxus brevifolia, ≥95% (HPLC), powder

Customers Also Viewed

(<I>S</I>)-(+)-Camptothecin

≥90% (HPLC), powder

Etoposide
E2600000Etoposide

European Pharmacopoeia (EP) Reference Standard

Irinotecan hydrochloride

topoisomerase inhibitor

Topotecan hydrochloride hydrate

≥98% (HPLC and enzymatic)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?