• USA Home
  • E2387 - 5′-(N-Ethylcarboxamido)adenosine

EMAIL THIS PAGE TO A FRIEND
E2387 Sigma

5′-(N-Ethylcarboxamido)adenosine

powder

Synonym: NECA

Purchase

Properties

Related Categories Adenosines/P2 Nucleotide Receptor - Agonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
InChI Key   JADDQZYHOWSFJD-FLNNQWSLSA-N
form   powder
color   white
solubility   45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.2 mg/mL (Solutions may be stored for several days at 4 °C.)
  DMSO: soluble14 mg/mL (Solutions may be stored for several days at 4 °C.)
  0.1 M HCl: soluble3.4 mg/mL (Solutions may be stored for several days at 4 °C.)
  H2O: insoluble
  ethanol: soluble (Solutions may be stored for several days at 4 °C.)
storage temp.   2-8°C
Gene Information   human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
rat ... Adora1(29290), Adora2a(25369), Adora2b(29316), Adora3(25370)

Description

Biochem/physiol Actions

Potent adenosine receptor agonist with nearly equal affinity at A1 and A2 receptors.

Packaging

50 mg in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
RTECS 
VJ2232000
Protocols & Articles

Articles

Fluorescent G protein-coupled receptors (GPCRs)

G protein-coupled receptors (GPCRs) are the largest class of transmembrane proteins and the targets for almost half of the clinical drugs in the market today. Advances in X-ray crystallography and ot...
Mike Earley, Market Segment Manager, Sigma Life Science
Biofiles Vol. 8, No. 4
Keywords: Clinical, Confocal microscopy, Ligands, Microscopy

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?