MDL number MFCD00162282
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| Related Categories | 2-2B, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, |
| species reactivity | mouse, pig, human, rat, canine |
| does not react with | rabbit |
| application(s) | indirect ELISA: 1:10,000 using extract of the A431 cell line |
| western blot: 1:3,000 using extract of the A431 cell line | |
| clone | 29.1, monoclonal |
| antibody form | ascites fluid |
| isotype | IgG1 |
| contains | 15 mM sodium azide |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information |
human ... EGFR(1956) mouse ... Egfr(13649) rat ... Egfr(24329) |
human carcinoma cell line A431, which expresses high levels of EGF receptors.
Localizes blood type A-related determinants on various glycoproteins and glycolipids in addition to specific EGF receptor determinants (only observed in human tissue). Binds an external carbohydrate on the receptor and does not block EGF binding.
May be used to purify EGF receptor, for structural and functional studies of the receptor and for investigation of cell transformation versus oncogenesis.
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