E2760 Sigma

Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse

clone 29.1, ascites fluid

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Properties

Related Categories 2-2B, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology,
species reactivity   mouse, pig, human, rat, canine
does not react with   rabbit
application(s)   indirect ELISA: 1:10,000 using extract of the A431 cell line
  western blot: 1:3,000 using extract of the A431 cell line
clone   29.1, monoclonal
antibody form   ascites fluid
isotype   IgG1
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... EGFR(1956)
mouse ... Egfr(13649)
rat ... Egfr(24329)

Description

Immunogen

human carcinoma cell line A431, which expresses high levels of EGF receptors.

Specificity

Localizes blood type A-related determinants on various glycoproteins and glycolipids in addition to specific EGF receptor determinants (only observed in human tissue). Binds an external carbohydrate on the receptor and does not block EGF binding.

Application

May be used to purify EGF receptor, for structural and functional studies of the receptor and for investigation of cell transformation versus oncogenesis.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Price and Availability

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