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E3380 Sigma

Ellipticine

synthetic

Synonym: 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole

  • CAS Number 519-23-3

  • Empirical Formula (Hill Notation) C17H14N2

  • Molecular Weight 246.31

  •  Beilstein Registry Number 221300

  •  EC Number 208-264-0

  •  MDL number MFCD00010524

  •  PubChem Substance ID 24278416

  • Popular Documents:  FTNMR (PDF)  

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Properties

biological source   synthetic
InChI Key   CTSPAMFJBXKSOY-UHFFFAOYSA-N
storage temp.   2-8°C
Gene Information   human ... CYP1A1(1543), CYP1A2(1544), KIT(3815), TOP2A(7153)

Description

Biochem/physiol Actions

Ellipticine is an antitumor alkaloid isolated from Ochrosia sp. It inhibits cytochrome P450 (CYP1A1) and DNA topoisomerase II activities.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


Flow Cytometry Instruments
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3462 6.1 / PGIII
WGK Germany 
3
RTECS 
UU8825000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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