• USA Home
  • E5017 - Anti-LPA1, C-Terminal antibody produced in rabbit

E5017 Sigma

Anti-LPA1, C-Terminal antibody produced in rabbit

~1 mg/mL, IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-EDG-2, Anti-Endothelial Cell Differentiation Gene 2



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Lipids in Cell Signaling, LM-LRP,
species reactivity   human, rat
application(s)   western blot: suitable
clone   polyclonal
concentration   ~1 mg/mL
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~50 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... LPAR1(1902)
rat ... Lpar1(116744)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 328-344 of human EDG-2/LPA1.

Physical form

Solution in 0.2 mM sterile-filtered Ca2+- and Mg2+- free Dulbecco′s PBS, containing 0.05% sodium azide


Anti-LPA1, C-Terminal antibody produced in rabbit is suitable for western blotting at a working dilution of 1:1000 using rat brain microsomal fraction.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

Lysophosphatidic acid receptor 1 (LPA1) is a protein encoded by the LPAR1 gene in humans. It is constitutively localized in the nucleus of mammalian cells and may be involved in regulating intranuclear protein phosphorylation and signalling. LPA1 is differentially expressed in androgen-insensitive and LPA-responsive cells. It is not expressed in androgen-dependent and LPA-resistant cells.Its expression is significantly higher in the cancer compared with the benign tissues and may possibly act as a drug target to interfere with progression of prostate cancer. LPA1 helps in promoting cell proliferation, survival and migration by acting on cognate G protein-coupled receptors.

Price and Availability

Antibody Explorer

Explore with Confidence
Safety & Documentation


Certificate of Analysis

Certificate of Origin

Safety Information

WGK Germany  -
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?