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  • E7525 - Anti-Ephrin-B2 antibody produced in goat

E7525 Sigma

Anti-Ephrin-B2 antibody produced in goat

affinity isolated antibody



Related Categories Alphabetical Index, Angiogenesis, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology,
species reactivity   mouse
application(s)   flow cytometry: 0.25 μg using 106 cells
  immunocytochemistry: 5-15 μg/mL
  western blot: 1 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
storage temp.   −20°C
Gene Information   mouse ... Efnb2(13642)
biological source   goat
conjugate   unconjugated



recombinant mouse ephrin-B2, expressed in NSO cells.

General description

By immunoblotting and ELISA, the antibody shows ~50% cross-reactivity with recombinant human ephrin-B5 and 15% cross-reactivity with mouse ephrin-B1.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4 with 5% trehalose.

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Biochem/physiol Actions

Ephrin B2 binds to EPH receptor B, a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. EphB receptors and EphrinB ligands have a regulatory effect on endothelial cell function, angiogenesis, migration, cell growth and survival.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  3
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