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ED4S Sigma

Ethylenediaminetetraacetic acid tetrasodium salt hydrate

practical grade, ≥95%

Synonym: EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate hydrate

  • CAS Number 194491-31-1

  • Linear Formula (NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O

  • Molecular Weight 380.17 (anhydrous basis)

  •  Beilstein Registry Number 3861753

  •  EC Number 200-573-9

  •  MDL number MFCD00150025

  •  PubChem Substance ID 24894710

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Description

Preparation Note

Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.

Application

EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.

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Amplified Detection
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Respiratory Tract
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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