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ED4SS Sigma

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate

99.0-102.0% (titration)

Synonym: EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate dihydrate



Related Categories Buffers, Calcium Chelators, Calcium Signaling Research Tools, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   PREMIUM
assay   99.0-102.0% (titration)
solubility   H2O: soluble, clear, colorless



Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.


1 kg in poly bottle

100, 500 g in poly bottle

2.5 kg in poly drum

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Target organs 
Respiratory Tract
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Protocols & Articles


Enzymatic Assay of Cathepsin B

This procedure applies to all products that have a specification for Cathepsin B activity, such as Sigma-Aldrich Product Numbers C0150 and C8571, determined by the liberation of 7-amino-4-methylcouma...
Keywords: Enzyme activity, Enzymology

Enzymatic Assay of Ficin (EC

The spectrophotometric stop rate detemination (A280, Light path = 1 cm) is based on the following reaction:

Enzymatic Assay of Lipase Type XIII from Pseudomonas Species and Pseudomonas Cepacia using a coupled enzyme system of Glycerol Kinase and Glycerophosphate Oxidase (EC

To standardize a procedure for the enzymatic assay of Lipase Type XIII from Pseudomonas Species, Sigma Product Number L9518 , and Pseudomonas Cepacia, Sigma Product Number L9156, using a coupled enzy...
Keywords: Centrifugation, Extinction coefficient, High performance liquid chromatography

Enzymatic Assay of α-Glucosidase by the Modified Boehenger Procedure (EC

To standardize a procedure for the enzymatic assay of α-glucosidase by the modified Boehenger procedure at Sigma-Aldrich St. Louis.
Keywords: Enzyme activity, Extinction coefficient

Recycling Micro-Assay of β-NAD and β-NADH

1. OBJECTIVE To standardize a procedure for the recycling micro-assay of β-NAD and β-NADH at Sigma-Aldrich Saint Louis.
Keywords: Sonication

Related Content

Immunohistochemistry Procedures

Immunohistochemical staining is a valuable tool for detecting specific antigens in tissues. In order to perform the standard staining procedure, first the tissue section has to be deparaffinized and ...
Keywords: Digestions, Immunohistochemistry, Solvents

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03695 Ethylenediaminetetraacetic acid tetrasodium salt dihydrate, purum, ≥98.0% (KT)
E6511 Ethylenediaminetetraacetic acid tetrasodium salt dihydrate, BioReagent, suitable for cell culture, 99.0-102.0%

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