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F0176 Sigma

Anti-FLI-1 antibody produced in sheep

fractionated antiserum, buffered aqueous solution

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Gene Regulation, Antibodies to Common Transcription Factors, Antibodies to Transcription Factors,
species reactivity   human, mouse
application(s)   western blot: suitable using whole extracts from mouse erythroleukemia cell lines, DP16-1 and CB7 and human T-cell line.
clone   polyclonal
antibody form   fractionated antiserum
form   buffered aqueous solution
mol wt   antigen mol wt 52 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... FLI1(2313)
mouse ... Fli1(14247)
biological source   sheep
conjugate   unconjugated

Description

Immunogen

GST fusion protein of the N-terminus of Fli-1 corresponding to amino acids 1-239.

Physical form

Solution in 0.01 M phosphate buffered saline, containing 0.08% sodium azide

Application

Anti-FLI-1 antibody produced in sheep is suitable for western blotting using whole extracts from mouse erythroleukemia cell lines, DP16-1 and CB7 and human T-cell line.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

Friend leukemia integration 1 transcription factor (FLI1) is a protein that is encoded by the FLI1 gene in humans and is a member of Ets transcription factor family. It is a proto-oncogene and located on human chromosome 11q23-24. FLI1 may be involved in human sarcomas, leukemias and lymphomas. It may play an important role in the posttranscriptional regulation of the Fli-1 transcript. Alteration in the transcriptional activation function of Fli-1 may be responsible for human malignancies. It is a novel ETS transcription factor involved in gene fusions in prostate cancer.

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Safety & Documentation

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

WGK Germany  2
Protocols & Articles

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Peer-Reviewed Papers
15

References

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