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  • F0307 - Anti-FHL1 (113-125) antibody produced in rabbit

F0307 Sigma

Anti-FHL1 (113-125) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-FHL1B, Anti-FLH1A, Anti-Four and a half LIM domains protein 1 isoform 1, Anti-KYO-T, Anti-SLIM1, Anti-XMPMA



Related Categories Alphabetical Index, Antibodies, FB-FJ, Primary Antibodies
species reactivity   human
application(s)   western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~32 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... FHL1(2273)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 113-125 of human FHL1

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Anti-FHL1 (113-125) antibody produced in rabbit is suitable for western blotting at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

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Biochem/physiol Actions

Four and a half LIM domains protein 1 is a protein encoded by the FHL1 gene in humans and is located on human chromosome Xq27.2. The proteins belong to a novel family of LIM proteins that are expressed in human skeletal muscle. FHL1 gene is related to carcinogenesis and its inactivation is a frequent event during oral carcinogenesis. FHL1 downregulation in oral squamous cell carcinoma (OSCC) occurs through DNA methylation of the promoter region rather than histone deacetylation or mutation.

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