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  • F1666 - Monoclonal Anti-Follicular Dendritic Cells antibody produced in mouse

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F1666 Sigma

Monoclonal Anti-Follicular Dendritic Cells antibody produced in mouse

buffered aqueous solution, purified immunoglobulin, clone HJ2, Immunohistology Grade

Synonym: Anti-FDC

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Properties

Related Categories Alphabetical Index, Antibodies, FK-FO, Primary Antibodies
biological source   mouse
antibody form   purified immunoglobulin
clone   HJ2, monoclonal
form   buffered aqueous solution
species reactivity   human
isotype   IgM
conjugate   unconjugated
storage temp.   2-8°C

Description

Features and Benefits

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Other Notes

FDC are phenotypically distinct cells that are restricted to lymphoid follicles and are morphologically large cells often containing multiple nuclei that exhibit numerous dendritic processes. Purified HJ2 positive cells exhibit various surface antigens whose expression by FDC has been firmly established. HJ2 positive cells are positive for CD54, VCAM-1, CD21, CD14, and Class II molecules, but are negative for ELAM-1, CD20, and CD2/CD3.

Immunogen

human tonsil cells

Specificity

Recognizes follicular dendritic cells (FDC) located in germinal centers (GC) in tonsil, spleen and Peyer′s patches.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

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Safety & Documentation

Safety Information

WGK Germany 
3
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
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Peer-Reviewed Papers
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F3803 Monoclonal Anti-Follicular Dendritic Cells (FDC) antibody produced in mouse, clone CNA.42, tissue culture supernatant

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