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  • F2258 - Fructose-6-phosphate Kinase, Pyrophosphate-dependent from potato tuber

F2258 Sigma

Fructose-6-phosphate Kinase, Pyrophosphate-dependent from potato tuber

lyophilized powder, ≥2 units/mg protein (Lowry)

Synonym: 6-Phosphofructokinase(pyrophosphate), Pyrophosphate: D-fructose-6-phosphate 1-phosphotransferase



Other Notes

These two pyrophosphate-dependent fructose-6-phosphate kinases differ in their response to the physiological activator fructose 2,6-diphosphate [Fru (2,6)-P2]. The enzyme from Propionibacterium freudenreichii (F8381) reportedly is not affected by Fru (2,6)-P2. The enzyme from potato tubers (F2258) is stimulated by Fru (2,6)-P2 (half-maximal activation at 5.5 nM Fru (2,6)-P2 for potato tuber enzyme).

Unit Definition

One unit will convert 1.0 μmole of pyrophosphate and fructose 6-phosphate to fructose 1,6-diphosphate and inorganic phosphate per min at pH 8.0 at 30 °C in the presence of 1μM fructose 2,6-diphosphate and 17 mM glucose 6-phosphate.

Physical form

Lyophilized powder containing sodium phosphate buffer and stabilizers with traces of inorganic pyrophosphate and dithiothreitol

Biochem/physiol Actions

Fructose-6-phosphate kinase converts fructose-6-phosphate into fructose 1,6-bisphophate in the rate limiting step of the glycolysis cycle.

Price and Availability

All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Protocols & Articles

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