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F3422 Sigma

Flt-3/Flk-2 ligand human

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE and HPLC)

Synonym: FL

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Description

Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.

General description

Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.

Physical form

Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS.

Biochem/physiol Actions

Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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