Fumonisin B2 from Fusarium moniliforme
sphingosine N-acyltransferase inhibitor
DOWNLOAD MSDS (PDF)-
CAS Number 116355-84-1
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Empirical Formula (Hill Notation) C34H59NO14
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Molecular Weight 705.83
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MDL number MFCD00133350
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PubChem Substance ID 24894857
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Popular Documents: Specification Sheet (PDF)
Properties
| Related Categories | Biochemicals and Reagents, Core Bioreagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, |
| storage temp. | −20°C |
Description
Biochem/physiol Actions
Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.
General description
Mycotoxin originally isolated from Fusarium sp, which grows on corn. Produces neural tube defects and craniofacial abnormalities in fetuses.1 Many strains of Aspergillus niger growing naturally on grapes are capable of producing fumonisin B2,2 so it is now a concern for human consumption of grapes, raisins, and wine.
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