|Related Categories||Biochemicals and Reagents, Core Bioreagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates,|
Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.
1, 10 mg in glass bottle
Mycotoxin originally isolated from Fusarium sp, which grows on corn. Produces neural tube defects and craniofacial abnormalities in fetuses.1 Many strains of Aspergillus niger growing naturally on grapes are capable of producing fumonisin B2,2 so it is now a concern for human consumption of grapes, raisins, and wine.
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50 μg/mL in acetonitrile: water, analytical standard, for environmental analysis
50 μg/mL in acetonitrile: water (50:50), analytical standard, for environmental analysis
Certificate of Analysis
Certificate of Origin
|Hazard statements||H300 +H310 + H330-H315-H319-H335-H351|
|Precautionary statements||P260-P264-P280-P284-P301 + P310-P302 + P350|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T+|
|Risk Statements (Europe)||26/27/28-36/37/38-40|
|Safety Statements (Europe)||22-36/37/39-45|
|RIDADR||UN 2811 6.1 / PGI|
1. Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize Marasas, W.F., et al. J. Nutr. 134, 711-716, (2004)
Relationship between fumonisin production and FUM gene expression in Fusarium verticillioides under different environmental conditions. Fanelli F, Iversen A, Logrieco AF, et al. Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 30(2), 365-71, (2013)
Analysis of fumonisins B1 and B2 in spices and aromatic and medicinal herbs by HPLC-FLD with on-line post-column derivatization and positive confirmation by LC-MS/MS. Kong W, Xie T, Li J, et al. Analyst 137(13), 3166-74, (2012)
[Simultaneous determination of fumonisins B1 and B2 in traditional Chinese medicines by high-performance liquid chromatography-tandem mass spectrometry]. Xie TT, Qiu F, Yang MH, et al. Yao Xue Xue Bao 46(7), 822-7, (2011)
Assessment of fumonisins B1 and B2 levels in commercial maize-based food products by liquid chromatography with fluorimetric detection and postcolumn chemical derivatization. Lo Magro S, Campaniello M, Nardiello D, et al. J. Food Sci. 76(1), T1-4, (2011)
Comparison of methods and optimisation of the analysis of fumonisins B₁ and B₂ in masa flour, an alkaline cooked corn product. De Girolamo A, Pascale M, and Visconti A Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 28(5), 667-75, (2011)
Molecular characterization and fumonisin production by Fusarium verticillioides isolated from corn grains of different geographic origins in Brazil. de Oliveira Rocha L, Reis GM, da Silva VN, et al. Int. J. Food Microbiol. 145(1), 9-21, (2011)
Occurrence of fumonisins in Catalonia (Spain) and an exposure assessment of specific population groups. Cano-Sancho G, Ramos AJ, Marín S, et al. Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 29(5), 799-808, (2012)
Determination of fumonisins B1 and B2 in corn-based foods for infants and young children by LC with immunoaffinity column cleanup: interlaboratory validation study. Solfrizzo M, De Girolamo A, Gambacorta L, et al. J. AOAC Int. 94(3), 900-8, (2011)
Fumonisin B1 and B2 occurrence in dried fig fruits (Ficus carica L.) under Meander Valley's climatic conditions and relationship with fruit quality. Kosoglu I, Aksoy U, and Pehlivan R Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 28(11), 1569-77, (2011)
Surveys of rice sold in Canada for aflatoxins, ochratoxin A and fumonisins. Bansal J, Pantazopoulos P, Tam J, et al. Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 28(6), 767-74, (2011)
Determination of fumonisins B₁ and B₂ in maize food products by a new analytical method based on high-performance liquid chromatography and fluorimetric detection with post-column derivatization. Muscarella M, Magro SL, Nardiello D, et al. Methods Mol. Biol. 739, 187-94, (2011)
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