EMAIL THIS PAGE TO A FRIEND
F3917 Sigma

Forskolin

For use in molecular biology applications

Synonym: 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one, Coleonol, Colforsin

Purchase

Properties

Related Categories Biochemicals, Biochemicals and Reagents, Isoprenoids, Lipids, Molecular Biology,
biological source   from Coleus forskohlii
description   for activation of T cells
InChI Key   OHCQJHSOBUTRHG-KGGHGJDLSA-N
product line   BioReagent
assay   ≥98% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: soluble5 mg/mL (stable at least 6 months at room temperature)(lit.)
  ethanol: soluble
suitability   suitable for inhibits interleukin 2 (IL-2) production in Jurkat cells
storage temp.   room temp

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Forskolin effects calcium currents and inhibits MAP kinase.

Packaging

10, 25 mg in poly bottle

General description

Forskolin is a cell permeable diterpenoid isolated from Coleus forskohlii.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
QL6150000
Protocols & Articles

Articles

Forskolin from Coleus forskohlii

T-cell activation is normally triggered by the interaction of a cell surface receptor to its specific ligand molecule. This binding event triggers the rapid hydrolysis of inositol phospholipids to di...
Keywords: Addition reactions, Centrifugation, Culture media, Enzyme-linked immunosorbent assay, Ligands, Phosphorylations

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

L8902 Lectin from Phaseolus vulgaris (red kidney bean), Phytohemagglutinin PHA-M, lyophilized powder, BioReagent, suitable for cell culture
I9516 2-Propanol, BioReagent, for molecular biology, ≥99.5%
D8418 Dimethyl sulfoxide, for molecular biology
P4557 Phenol solution, Equilibrated with 10 mM Tris HCl, pH 8.0, 1 mM EDTA, BioReagent, for molecular biology
P1585 PMA, for use in molecular biology applications, ≥99% (TLC)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?