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F5178 Sigma

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

Synonym: FMO-5

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Drug Metabolism Enzymes and Reagents; Cyp 450s, Oxidases and Reductases, Drug and Xenobiotic Metabolism,
recombinant   expressed in baculovirus infected insect cells
form   buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
packaging   vial of 2.5 mg
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... FMO5(2330)

Description

Application

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Physical form

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Biochem/physiol Actions

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

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All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
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